Wannemacher R W, Dinterman R E, Rayfield E J, Beisel W R
Am J Clin Nutr. 1977 Apr;30(4):573-8. doi: 10.1093/ajcn/30.4.573.
After an intravenous glucose load in man, total serum amino acid concentrations are rapidly depressed and remain below baseline values for at least 2 to 3 hr after serum glucose and insulin have returned to preload concentrations. Despite the presence of basal hypoaminoacidemia, a decreased glucose disappearance rate, and hyperinsulinemia in volunteers who were ill with sandfly fever, an intravenous glucose load resulted in a further depression of serum amino acids which was equal to or slightly greater than that observed in the same individuals before exposure to the virus. Although the infectious process may have some effect on insulin-stimulated hepatic disposal of a glucose load, it does not appear to influence the ability on insulin to decrease the rate of release of certain amino acids from skeletal muscle.
在人体静脉注射葡萄糖负荷后，血清总氨基酸浓度迅速下降，并且在血清葡萄糖和胰岛素恢复到负荷前浓度后至少2至3小时内一直低于基线值。尽管患有白蛉热的志愿者存在基础低氨基酸血症、葡萄糖消失率降低和高胰岛素血症，但静脉注射葡萄糖负荷仍导致血清氨基酸进一步下降，这与在这些个体接触病毒之前观察到的情况相等或略高。虽然感染过程可能对胰岛素刺激的肝脏对葡萄糖负荷的处理有一定影响，但似乎并不影响胰岛素降低某些氨基酸从骨骼肌释放速率的能力。
