Senior Department of Burns and Plastic Surgery, the Fourth Medical Center of Chinese PLA General Hospital, Beijing, China.
Int Wound J. 2023 May;20(5):1725-1738. doi: 10.1111/iwj.13988. Epub 2022 Oct 23.
Pathological scar is a classic problem in plastic and reconstructive surgery. Although the researches on pathological scar have been conducted for decades, the way to go to address this thorny problem still remains challenging. To the best of our knowledge, few bibliometric analysis concerning pathological scar have been reported. In this study, we set out to employ bibliometric and visual analysis to offer research status and trends of pathological scar over the period 2001-2021. All publications covering pathological scar during 2001-2021 were retrieved and extracted from the Web of Science database. We applied VOSviewer software to evaluate the keywords and research hotpots, and the online tool (http://bibliometric.com/) was used to carried out the publication trends analysis. A total of 2221 pathological scar-related articles were identified over the period 2001-2021. China is the country which had the largest volume of publications (819, 36.87%), followed by the United States (416, 18.73%), Japan (144, 6.48%), Korea (142, 6.39%), and England (118, 5.31%). Among the institutions and journals, Shanghai Jiao Tong University (167) and Wound Repair and Regeneration (85) accounted for the most papers related to pathological scar, respectively. Professor Bayat A, who had the most citation frequency (2303), made great contribution in pathological scar field. "Fibroblast", "expression", and "proliferation" were identified as the pathological scar research hotspot through analysis of the keywords. In terms of publication, China ranked first all over the world, but the numbers of publication are inconsistent with the citation frequency, ranking first and second, respectively. Shanghai Jiao Tong University and journal Wound Repair and Regeneration stand for the highest level of research in this field to a certain extent. In the early stage, the research focus was mainly on the prevention, treatment, and risk factors for recurrence of pathological scar from cases. In the later stage, the research focus was on the comprehensive management, in which the mechanism research was in-depth to the molecular and gene level.
病理性瘢痕是整形重建外科的一个经典问题。尽管对病理性瘢痕的研究已经进行了几十年，但解决这个棘手问题的方法仍然具有挑战性。据我们所知，很少有关于病理性瘢痕的文献计量分析报道。在本研究中，我们采用文献计量学和可视化分析方法，对 2001-2021 年期间病理性瘢痕的研究现状和趋势进行研究。从 Web of Science 数据库中检索并提取了 2001-2021 年间所有关于病理性瘢痕的出版物。我们应用 VOSviewer 软件评估关键词和研究热点，并使用在线工具（http://bibliometric.com/）进行出版物趋势分析。共确定了 2001-2021 年间 2221 篇与病理性瘢痕相关的文章。中国是发表文章数量最多的国家（819 篇，占 36.87%），其次是美国（416 篇，占 18.73%）、日本（144 篇，占 6.48%）、韩国（142 篇，占 6.39%）和英国（118 篇，占 5.31%）。在机构和期刊中，上海交通大学（167 篇）和《创伤修复与再生》（85 篇）发表的与病理性瘢痕相关的论文最多。Bayat A 教授的引用频次（2303）最高，他在病理性瘢痕领域做出了巨大贡献。通过关键词分析，确定了“成纤维细胞”、“表达”和“增殖”为病理性瘢痕研究热点。在出版物方面，中国在全球排名第一，但出版物数量与引文频率不一致，分别排名第一和第二。上海交通大学和期刊《创伤修复与再生》在一定程度上代表了该领域的最高研究水平。在早期，研究重点主要集中在病理性瘢痕的预防、治疗和复发风险因素方面。在后期，研究重点转向综合管理，对机制的研究深入到分子和基因水平。
