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鼻上颌毛霉菌病的治疗:一例报告

Management of Rhinomaxillary Mucormycosis: A Case Report.

作者信息

Khandaitkar Sandeep, Harde Komal, Khan Sharjeel H, Lamba Gagandeep

机构信息

Department of Oral and Maxillofacial Surgery, Ranjeet Deshmukh Dental College and Research Centre, Nagpur, IND.

Department of Oral and Maxillofacial Surgery, Swargiya Dadasaheb Kalmegh (SDK) Smruti Dental College and Hospital, Nagpur, IND.

出版信息

Cureus. 2025 Apr 15;17(4):e82299. doi: 10.7759/cureus.82299. eCollection 2025 Apr.

Abstract

This case report describes a rare occurrence of palatal mucormycosis in a 45-year-old immunocompetent female patient who developed black discoloration of the palate following a tooth extraction. Initial diagnostic investigations and superficial biopsy revealed aspergillosis; however, further postoperative histopathological examination confirmed mucormycosis. Aggressive surgical intervention, including maxillectomy, alveolectomy, and functional endoscopic sinus surgery, combined with targeted antifungal therapy, facilitated successful treatment. The importance of timely diagnosis and comprehensive management in mucormycosis cases, even among immunocompetent patients, is highlighted.

摘要

本病例报告描述了一名45岁免疫功能正常的女性患者罕见的腭部毛霉菌病,该患者在拔牙后腭部出现黑色变色。初步诊断检查和浅表活检显示为曲霉菌病;然而,术后进一步的组织病理学检查确诊为毛霉菌病。积极的手术干预,包括上颌骨切除术、牙槽骨切除术和功能性鼻内镜鼻窦手术,联合靶向抗真菌治疗,促成了成功治疗。强调了在毛霉菌病病例中及时诊断和综合管理的重要性,即使在免疫功能正常的患者中也是如此。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/28dc/12080622/0bb2fd7f9f9e/cureus-0017-00000082299-i01.jpg

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