Ponce Dawson Silvina
Physics Department, UBA-FCEN, Ciudad Universitaria, Pab I, Buenos Aires, 1428 Argentina.
IFIBA, CONICET-UBA, Ciudad Universitaria, Pab I, Buenos Aires, 1428 Argentina.
Biophys Rev. 2025 Apr 10;17(2):271-283. doi: 10.1007/s12551-025-01308-8. eCollection 2025 Apr.
In this report, I describe some of the subjects and problems that we have addressed over the last 25 years in the area of cell signaling using the tools of biological physics. The report covers part of our work on intracellular Ca signals, pattern formation, transport of messengers in the interior of cells, quantification of biophysical parameters from experiments, and information transmission. The description includes both our modeling and experimental work highlighting how the tools of physics can give useful insights into the workings of biological systems.
在本报告中,我描述了过去25年来我们运用生物物理学工具在细胞信号传导领域所涉及的一些主题和问题。该报告涵盖了我们在细胞内钙信号、模式形成、细胞内信使运输、从实验中量化生物物理参数以及信息传递等方面的部分工作。描述内容包括我们的建模和实验工作,突出了物理学工具如何能为生物系统的运作提供有用的见解。