Mohamed Ibrahim Abdullahi, Omar Abdullahi Abdirahman, Hassan Mulki Mukhtar, Hassan Mohamed Abdulahi, Adan Zakaria Mohamed, Mohamed Zubeir Abdulkadir
Dr. Sumait Hospitals, Faculty Medicine and Health Sciences, SIMAD University, Mogadishu, Somali.
Faculty Medicine and Health Sciences, SIMAD University, Mogadishu, Somalia.
Int Med Case Rep J. 2025 May 11;18:545-551. doi: 10.2147/IMCRJ.S516956. eCollection 2025.
Intracerebral hemorrhage (ICH) is a rare but severe complication of preeclampsia, significantly contributing to maternal morbidity and mortality, particularly in resource-limited settings. The underlying mechanisms include endothelial dysfunction, cerebral autoregulation failure, and breakdown of the blood-brain barrier. This case report aims to highlight a unique presentation of severe preeclampsia complicated by ICH, emphasizing barriers encountered in resource-limited settings and discussing long-term implications and prognosis.
A 35-year-old multiparous woman presented two days postpartum with altered mental status, aphasia, and right-sided hemiparesis. Her pregnancy was complicated by severe preeclampsia and intrauterine fetal death. Computed tomography (CT) revealed a left basal ganglia hemorrhage extending into the ventricles. She received conservative management including antihypertensive medications, magnesium sulfate for seizure prophylaxis, and anti-edema therapy. Despite limited diagnostic resources, laboratory evaluations ruled out coagulopathies and vascular anomalies. After 20 days of multidisciplinary care, significant neurological recovery was achieved. Follow-up after four weeks demonstrated complete functional recovery, with resolution confirmed by repeat CT.
This case uniquely underscores the critical importance of timely multidisciplinary care and robust antenatal monitoring in mitigating severe complications such as ICH associated with preeclampsia. The patient's full recovery highlights the potential for successful conservative management even in resource-constrained environments. Future clinical practice and research should focus on improving antenatal care accessibility, patient education, and developing context-specific management guidelines to reduce maternal morbidity and mortality in similar settings.
脑出血(ICH)是先兆子痫一种罕见但严重的并发症,对孕产妇的发病率和死亡率有显著影响,在资源有限的地区尤其如此。其潜在机制包括内皮功能障碍、脑自动调节功能衰竭和血脑屏障破坏。本病例报告旨在突出先兆子痫并发脑出血的独特表现,强调资源有限环境中遇到的障碍,并讨论其长期影响和预后。
一名35岁经产妇产后两天出现精神状态改变、失语和右侧偏瘫。她的妊娠合并严重先兆子痫和宫内胎儿死亡。计算机断层扫描(CT)显示左侧基底节区出血并延伸至脑室。她接受了包括抗高血压药物、硫酸镁预防癫痫发作和抗水肿治疗在内的保守治疗。尽管诊断资源有限,但实验室检查排除了凝血功能障碍和血管异常。经过20天的多学科护理,患者神经功能有显著恢复。四周后的随访显示功能完全恢复,复查CT证实了这一点。
本病例独特地强调了及时的多学科护理和强有力的产前监测在减轻与先兆子痫相关的脑出血等严重并发症方面的至关重要性。患者的完全康复突出了即使在资源有限的环境中进行成功保守治疗的可能性。未来的临床实践和研究应侧重于提高产前护理的可及性、患者教育,并制定针对具体情况的管理指南,以降低类似环境下的孕产妇发病率和死亡率。