Bejar J M, Kerby G R, Ziegler D K, Festoff B W
Ann Neurol. 1985 Aug;18(2):258-60. doi: 10.1002/ana.410180214.
This report documents the twelve-year follow-up of a patient with neurosarcoidosis with multiple progressive central nervous system manifestations. Increased somnolence and seizure activity were associated with proliferation of nodular enhancing brain lesions, as seen on serial computed tomographic (CT) scans. Initially he responded to corticosteroid treatment, but gradually this response became unsatisfactory. After whole-brain irradiation with a total dose of 3,000 rads, his clinical symptoms improved with disappearance of the enhancing brain lesions seen on CT scan.
本报告记录了一名患有神经结节病且有多种进行性中枢神经系统表现的患者的12年随访情况。如系列计算机断层扫描（CT）所示，嗜睡增加和癫痫活动与结节状强化脑病变的增殖有关。最初他对皮质类固醇治疗有反应，但逐渐这种反应变得不尽人意。在全脑照射总剂量达3000拉德后，他的临床症状有所改善，CT扫描上可见的强化脑病变消失。
