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打破循环:预测儿童和青少年住院精神科的激越危机

Breaking the Cycle: Predicting Agitation Crises in Child and Adolescent Inpatient Psychiatry.

作者信息

Burns Ricky, Lynch Sean T, Staudenmaier Paige, Becker Timothy D, Shanker Parul, Martin Dalton, Leong Alicia, Rice Timothy

机构信息

Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

Department of Psychiatry, Mount Sinai Behavioral Health Center, 45 Rivington Street, New York, NY, 10002, USA.

出版信息

Child Psychiatry Hum Dev. 2025 May 16. doi: 10.1007/s10578-025-01852-0.

DOI:10.1007/s10578-025-01852-0
PMID:40377832
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12354062/
Abstract

This study examined biopsychosocial factors associated with the use of intramuscular (IM) agitation emergency medication in child and adolescent psychiatric inpatients. A retrospective review of 1,101 patients hospitalized between June 2018-November 2021 at an urban teaching hospital identified predictors of IM medication use through linear regression analysis. Among these patients, 196 received IM medication during their stay. Female sex was associated with a lower likelihood of receiving IM treatment, while factors such as prior involvement with child protective services, a history of violence, previous psychiatric hospitalizations, and use of multiple home psychiatric medications increased the likelihood. Agitation episodes pose risks to both patients and staff, underscoring the importance of early identification and intervention. Understanding these risk factors may guide proactive strategies to reduce the frequency and severity of agitation and limit reliance on emergency pharmacological interventions. Further research is needed to refine predictive models and explore non-pharmacological management approaches.

摘要

本研究调查了与儿童和青少年精神科住院患者使用肌内注射(IM)抗躁狂应急药物相关的生物心理社会因素。通过对一家城市教学医院在2018年6月至2021年11月期间住院的1101名患者进行回顾性研究,采用线性回归分析确定了使用IM药物的预测因素。在这些患者中,196人在住院期间接受了IM药物治疗。女性接受IM治疗的可能性较低,而诸如之前与儿童保护服务机构有过接触、暴力史、既往精神科住院史以及使用多种家庭精神科药物等因素会增加接受IM治疗的可能性。躁狂发作对患者和工作人员都构成风险,这凸显了早期识别和干预的重要性。了解这些风险因素可能会指导采取积极策略,以减少躁狂发作的频率和严重程度,并限制对应急药物干预的依赖。需要进一步研究以完善预测模型并探索非药物管理方法。

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本文引用的文献

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Predictors and Correlates of Psychiatric Polypharmacy Among Child and Adolescent Psychiatric Inpatients: A Retrospective Study.儿童和青少年精神科住院患者精神药物联合使用的预测因素及相关因素:一项回顾性研究
J Clin Psychopharmacol. 2025;45(3):243-250. doi: 10.1097/JCP.0000000000001981. Epub 2025 Mar 26.
2
Validity of Cognitive Disengagement Syndrome with Mother and Father Ratings of Brazilian Children: Replication of Northern Hemisphere Findings in South America.巴西儿童母亲和父亲评定的认知脱离综合征的有效性:在南美洲复制北半球的研究结果。
Child Psychiatry Hum Dev. 2024 Nov 29. doi: 10.1007/s10578-024-01789-w.
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Psychiatric crises among youth with a history of trauma during COVID-19: A retrospective study of psychiatrically hospitalized children and adolescents.新冠疫情期间有创伤史青少年的精神危机:一项针对精神科住院儿童及青少年的回顾性研究
Child Abuse Negl. 2024 Dec;158:107134. doi: 10.1016/j.chiabu.2024.107134. Epub 2024 Nov 7.
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Digital Media-related Problems Contributing to Psychiatric Hospitalizations Among Children and Adolescents Before and After the Onset of the COVID-19 Pandemic.新冠疫情爆发前后导致儿童和青少年因数字媒体相关问题而住院治疗的情况
Child Psychiatry Hum Dev. 2024 Jan 23. doi: 10.1007/s10578-024-01670-w.
5
Predictors and Correlates of Positive Urine Drug Screening in a Retrospective Cohort Analysis of Child and Adolescent Psychiatry Inpatients Throughout the COVID-19 Pandemic.在 COVID-19 大流行期间对儿童和青少年精神病学住院患者进行回顾性队列分析,探讨尿液药物筛查阳性的预测因素和相关性。
Subst Use Addctn J. 2024 Jan;45(1):33-43. doi: 10.1177/29767342231210711.
6
Characterization of Psychiatric Inpatients: The Role of Gender Differences in Clinical and Pharmacological Patterns.精神科住院患者的特征:性别差异在临床和药物治疗模式中的作用。
J Psychiatr Pract. 2024 Jan 1;30(1):2-12. doi: 10.1097/PRA.0000000000000756.
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Arch Womens Ment Health. 2023 Dec;26(6):777-783. doi: 10.1007/s00737-023-01360-x. Epub 2023 Aug 25.
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Psychiatry Res. 2023 Sep;327:115368. doi: 10.1016/j.psychres.2023.115368. Epub 2023 Jul 24.
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