Kardashian J L, Zackheim H S, Egbert B M
Arch Dermatol. 1985 Sep;121(9):1175-80.
A 47-year-old black man had typical papulonodular lesions of lymphomatoid papulosis (LyP) with concurrent plaque-stage mycosis fungoides (MF). Both diagnoses were confirmed histologically. This supports the concept that LyP is part of the spectrum of cutaneous T-cell lymphoproliferative disorders. The patient also had a large nodule and a deeply infiltrated plaque, each of which exhibited a deep granulomatous reaction. These were interpreted as representing granulomatous MF. Clinically, there was an evolution from a predominance of LyP lesions to a predominance of MF plaques. Topical carmustine therapy resulted in a substantial decrease in the number and size of both LyP and MF lesions. Both lesion types involuted with hypopigmentation.
一名47岁的黑人男性患有淋巴瘤样丘疹病（LyP）典型的丘疹结节性损害，并同时伴有斑块期蕈样肉芽肿（MF）。两种诊断均经组织学证实。这支持了LyP是皮肤T细胞淋巴增殖性疾病谱一部分的概念。该患者还有一个大结节和一个深部浸润性斑块，每一个都表现出深部肉芽肿反应。这些被解释为代表肉芽肿性MF。临床上，有从以LyP损害为主向以MF斑块为主的演变。局部用卡莫司汀治疗导致LyP和MF损害的数量和大小显著减少。两种损害类型均消退并伴有色素减退。
