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瑜伽练习对高血压患者生理和生化参数的影响:一项临床试验的系统评价

Effects of yogic practices on physiological and biochemical parameters of hypertensive patients: A systematic review of clinical trials.

作者信息

Tyagi Prakhar, Jain Khushbu

机构信息

Morarji Desai National Institute of Yoga, Ministry of Ayush, Govt. of India, New Delhi, India.

Morarji Desai National Institute of Yoga, Ministry of Ayush, Govt. of India, New Delhi, India.

出版信息

J Ayurveda Integr Med. 2025 May 15;16(3):101087. doi: 10.1016/j.jaim.2024.101087.

Abstract

BACKGROUND

Hypertension affects around 1.28 billion adults worldwide. If not managed properly, it can lead to life threatening conditions. While various pharmacological treatments are available, they are associated with various short- and long-term side effects. Hence it is crucial to explore alternative approaches to complement the standard medical interventions.

OBJECTIVE

This systematic review aims to explore the impacts of yogic practices on various physiological and biochemical parameters in hypertensive patients.

METHODS

Various electronic databases including PubMed, Cochrane library, Directory of Open Access Journals and Google scholar were systematically searched until October 31, 2023 to collect relevant data.

RESULTS

A total of 15 articles comprising 5 RCTs and 10 clinical trials were identified. The number of participants ranged between 33 and 300, with Yoga intervention lasting from two months to a year. The analyses revealed that Yogic practices, such as loosening practices, Surya Namaskar, Tadasana, Trikonasana, Paschimottanasana, Shavasana. Anulom-Vilom Pranayama, Bhramari Pranayama, meditation and Yoga Nidra, positively influenced physiological and biochemical markers linked to Hypertension such as autonomic nervous system activity, angiotensin II expression, oxidative stress, lipid metabolism, immune system function and inflammatory gene expression.

CONCLUSION

The findings of this systematic review indicate that the Yoga practices have a positive impact on physiological and biochemical markers associated with hypertension which may help in its proper management and treatment. Future studies need to assess additional markers associated with hypertension, such as vasopressin, adrenocorticotropic hormone, gamma-aminobutyric acid and others to enhance the understanding of the mechanism of the effects of Yoga on hypertension.

STUDY REGISTRATION

PROSPERO ID: CRD42024497060.

摘要

背景

全球约有12.8亿成年人患有高血压。如果管理不当,可能会导致危及生命的状况。虽然有多种药物治疗方法,但它们都伴有各种短期和长期副作用。因此,探索替代方法以补充标准医疗干预措施至关重要。

目的

本系统评价旨在探讨瑜伽练习对高血压患者各种生理和生化参数的影响。

方法

系统检索了包括PubMed、Cochrane图书馆、开放获取期刊目录和谷歌学术在内的各种电子数据库,直至2023年10月31日,以收集相关数据。

结果

共识别出15篇文章,包括5项随机对照试验和10项临床试验。参与者人数在33至300人之间,瑜伽干预持续时间为两个月至一年。分析表明,诸如放松练习、太阳致敬式、山式、三角式、坐立前屈式、挺尸式、腹式呼吸法、蜂鸣呼吸法、冥想和瑜伽休息术等瑜伽练习,对与高血压相关的生理和生化指标产生了积极影响,如自主神经系统活动、血管紧张素II表达、氧化应激、脂质代谢、免疫系统功能和炎症基因表达。

结论

本系统评价的结果表明,瑜伽练习对与高血压相关的生理和生化指标有积极影响,这可能有助于高血压的合理管理和治疗。未来的研究需要评估与高血压相关的其他指标,如血管加压素、促肾上腺皮质激素、γ-氨基丁酸等,以加深对瑜伽治疗高血压作用机制的理解。

研究注册

PROSPERO注册号:CRD42024497060。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a7ff/12145764/92a34cf9b236/gr1.jpg

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