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How JAK inhibitors tip the prothrombotic balance in rheumatoid arthritis.

作者信息

Strand Vibeke

机构信息

Division of Immunology and Rheumatology, Stanford University, Palo Alto, CA, USA.

出版信息

Nat Rev Rheumatol. 2025 May 16. doi: 10.1038/s41584-025-01263-4.

DOI:10.1038/s41584-025-01263-4
PMID:40379876
Abstract
摘要

相似文献

1
How JAK inhibitors tip the prothrombotic balance in rheumatoid arthritis.JAK抑制剂如何打破类风湿关节炎的促血栓平衡。
Nat Rev Rheumatol. 2025 May 16. doi: 10.1038/s41584-025-01263-4.
2
The Risk of Infections Associated With JAK Inhibitors in Rheumatoid Arthritis: A Systematic Review and Network Meta-analysis.类风湿关节炎中 JAK 抑制剂相关感染风险:系统评价和网络荟萃分析。
J Clin Rheumatol. 2022 Mar 1;28(2):e407-e414. doi: 10.1097/RHU.0000000000001749.
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Effect of JAK inhibitors on high- and low-density lipoprotein in patients with rheumatoid arthritis: a systematic review and network meta-analysis.JAK抑制剂对类风湿关节炎患者高密度脂蛋白和低密度脂蛋白的影响:一项系统评价和网状Meta分析
Clin Rheumatol. 2022 Mar;41(3):677-688. doi: 10.1007/s10067-021-06003-z. Epub 2022 Jan 7.
4
The efficacy and safety of different Janus kinase inhibitors as monotherapy in rheumatoid arthritis: A Bayesian network meta-analysis.不同 Janus 激酶抑制剂单药治疗类风湿关节炎的疗效和安全性:一项贝叶斯网状荟萃分析。
PLoS One. 2024 Jun 21;19(6):e0305621. doi: 10.1371/journal.pone.0305621. eCollection 2024.
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Cochrane Database Syst Rev. 2010 May 12(5):CD007648. doi: 10.1002/14651858.CD007648.pub2.
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Autoimmun Rev. 2023 Jul;22(7):103357. doi: 10.1016/j.autrev.2023.103357. Epub 2023 May 6.
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Cardiovascular safety of the class of JAK inhibitors or tocilizumab compared with TNF inhibitors in patients with rheumatoid arthritis: Systematic review and a traditional and Bayesian network meta-analysis of randomized clinical trials.与肿瘤坏死因子抑制剂相比,类风湿关节炎患者中JAK抑制剂或托珠单抗类药物的心血管安全性:随机临床试验的系统评价以及传统和贝叶斯网络荟萃分析
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The JAK-STAT pathway: an emerging target for cardiovascular disease in rheumatoid arthritis and myeloproliferative neoplasms.JAK-STAT 通路:类风湿关节炎和骨髓增殖性肿瘤中心血管疾病的新兴靶点。
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本文引用的文献

1
Adverse cardiovascular events in rheumatoid arthritis patients treated with JAK inhibitors: An analysis of postmarketing spontaneous safety reports.JAK 抑制剂治疗类风湿关节炎患者的心血管不良事件:上市后自发安全性报告分析。
Semin Arthritis Rheum. 2024 Aug;67:152461. doi: 10.1016/j.semarthrit.2024.152461. Epub 2024 May 17.
2
Venous thromboembolism with JAK inhibitors and other immune-modulatory drugs: a Swedish comparative safety study among patients with rheumatoid arthritis.静脉血栓栓塞症与 JAK 抑制剂和其他免疫调节药物:一项在类风湿关节炎患者中进行的瑞典比较安全性研究。
Ann Rheum Dis. 2023 Feb;82(2):189-197. doi: 10.1136/ard-2022-223050. Epub 2022 Sep 23.
3
Risk of venous thromboembolism in rheumatoid arthritis, and its association with disease activity: a nationwide cohort study from Sweden.
类风湿关节炎的静脉血栓栓塞风险及其与疾病活动的关系:来自瑞典的全国性队列研究。
Ann Rheum Dis. 2021 Feb;80(2):169-175. doi: 10.1136/annrheumdis-2020-218419. Epub 2020 Oct 8.
4
Incidence of venous and arterial thromboembolic events reported in the tofacitinib rheumatoid arthritis, psoriasis and psoriatic arthritis development programmes and from real-world data.托法替布在类风湿性关节炎、银屑病和银屑病关节炎研发项目以及真实世界数据中报告的静脉和动脉血栓栓塞事件的发生率。
Ann Rheum Dis. 2020 Nov;79(11):1400-1413. doi: 10.1136/annrheumdis-2019-216761. Epub 2020 Aug 5.
5
Cardiovascular Safety During Treatment With Baricitinib in Rheumatoid Arthritis.巴瑞替尼治疗类风湿关节炎的心血管安全性。
Arthritis Rheumatol. 2019 Jul;71(7):1042-1055. doi: 10.1002/art.40841. Epub 2019 May 25.