Akgun Gulsah Gumus, Kanik Selahattin Emirhan, Altan Cigdem, Alagoz Nese, Cakir Ihsan, Yasar Tekin
University of Health Sciences, Beyoglu Eye Training and Research Hospital, Bereketzade Cami Sk. No:2, 34421, Beyoğlu, İstanbul, Turkey.
Int Ophthalmol. 2025 May 17;45(1):195. doi: 10.1007/s10792-025-03561-y.
This study aims to compare one-year results and success rates of trabeculectomy and gonioscopy-assisted transluminal trabeculotomy (GATT) in eyes with long axial length (AL) and glaucoma.
This retrospective study included patients with an AL greater than 24 mm who underwent trabeculectomy (29 eyes) or GATT surgery (33 eyes) in our hospital and had at least a one-year follow-up. Complete success was defined as achieving an IOP > 5 and ≤ 21 mmHg (criterion A), > 5 and ≤ 18 mmHg (criterion B), or > 5 and ≤ 15 mmHg (criterion C), without the use of antiglaucoma medications or additional surgical interventions, except for bleb needling. The same IOP levels with or without medication were considered as overall success.
The GATT group required significantly more antiglaucoma medications at the 1-week, 1-month, and 3-month follow-ups (p < 0.05 for all). Complete success rates were higher in the trabeculectomy group based on criteria A, B, and C (p < 0.05 for each), and the overall success rates based on criteria A, B, and C were similar in both groups in one-year follow-up (p > 0.05 for each). The failure rates based on all three criteria were similar in both groups (p > 0.05 for each). The cumulative probability of overall success based on criterion B was 93.1, 86.2 and 79.3% at 3, 6 and 12 months in the trabeculectomy group and 90.9, 84.5 and 81.8% at 3, 6 and 12 months in the GATT group. The incidence of postoperative complications was higher in the GATT group, and the majority of complications were haemorrhage-related.
In eyes with long AL, the requirement for antiglaucoma medications is reduced in the first three months following trabeculectomy compared to GATT. Although the overall success rate was similar in both groups, the complete success rates of criteria A, B and C were higher in the trabeculectomy group. GATT may be considered an alternative in eyes with long AL.
本研究旨在比较小梁切除术和房角镜辅助的经腔小梁切开术(GATT)在眼轴长度(AL)较长且患有青光眼的眼中的一年期结果和成功率。
这项回顾性研究纳入了我院接受小梁切除术(29只眼)或GATT手术(33只眼)且眼轴长度大于24mm且至少随访一年的患者。完全成功定义为眼压>5且≤21mmHg(标准A)、>5且≤18mmHg(标准B)或>5且≤15mmHg(标准C),无需使用抗青光眼药物或进行额外的手术干预,但不包括房水滤过泡针刺。无论是否使用药物,相同的眼压水平被视为总体成功。
GATT组在1周、1个月和3个月随访时需要显著更多的抗青光眼药物(所有p<0.05)。根据标准A、B和C,小梁切除术组的完全成功率更高(每项p<0.05),在一年随访中,基于标准A、B和C的两组总体成功率相似(每项p>0.05)。基于所有三个标准的失败率在两组中相似(每项p>0.05)。小梁切除术组基于标准B的总体成功累积概率在3、6和12个月时分别为93.1%、86.2%和79.3%,GATT组在3、6和12个月时分别为90.9%、84.5%和81.8%。GATT组术后并发症发生率更高,且大多数并发症与出血相关。
在眼轴长度较长的眼中,与GATT相比,小梁切除术后前三个月对抗青光眼药物的需求减少。尽管两组的总体成功率相似,但小梁切除术组基于标准A、B和C的完全成功率更高。对于眼轴长度较长的眼,GATT可被视为一种替代方法。