Suppr超能文献

白内障手术中的前房内用药

Intracameral medications in cataract surgery.

作者信息

Bektas Caglar, Yuksel Erdem

机构信息

Department of Ophthalmology, Canakkale Onsekiz Mart University Faculty of Medicine, Canakkale, Turkey.

Department of Ophthalmology, Gazi University Faculty of Medicine, Ankara, Turkey.

出版信息

Int Ophthalmol. 2025 May 17;45(1):192. doi: 10.1007/s10792-025-03554-x.

Abstract

PURPOSE

To review the indications, dosages, and safety profiles of intracameral drugs used during cataract surgery.

METHODS

A narrative review was conducted, evaluating published clinical studies, review articles, and guidelines related to intracameral drug use in cataract surgery. The analysis focused on drugs commonly used for anesthesia, mydriasis, inflammation control, and intraoperative complication management. Special consideration was given to their utility in high-risk surgical scenarios, such as small pupils, intraoperative floppy iris syndrome, white or pediatric cataracts, and cases with zonular weakness.

RESULTS

Intracameral drugs have proven beneficial in achieving effective anesthesia, maintaining pupil dilation, and controlling inflammation during cataract surgery. Their use is particularly advantageous in complex cases, including those with corneal opacity, posterior capsular rupture, or combined procedures like minimally invasive glaucoma surgery and premium IOL implantation. When prepared and administered properly, these agents contribute to safer and more efficient surgeries. However, improper preparation or dosing can lead to ocular toxicity, highlighting the importance of meticulous handling.

CONCLUSION

Intracameral drug administration is a valuable adjunct in cataract surgery, enabling surgeons to manage routine and complex cases more effectively. Understanding their appropriate use and potential risks is essential to maximize patient safety and surgical success.

摘要

目的

回顾白内障手术中前房内使用药物的适应证、剂量及安全性。

方法

进行叙述性综述,评估已发表的关于白内障手术中前房内用药的临床研究、综述文章及指南。分析聚焦于常用于麻醉、散瞳、控制炎症及处理术中并发症的药物。特别考虑了它们在高风险手术场景中的效用,如小瞳孔、术中虹膜松弛综合征、白色或儿童白内障以及晶状体悬韧带薄弱的病例。

结果

前房内药物已被证明在白内障手术中有助于实现有效麻醉、维持瞳孔散大及控制炎症。它们在复杂病例中尤其具有优势,包括伴有角膜混浊、后囊膜破裂的病例,或如微创青光眼手术及高端人工晶状体植入等联合手术。当正确配制和给药时,这些药物有助于实现更安全、高效的手术。然而,配制不当或剂量错误可能导致眼毒性,凸显了精细操作的重要性。

结论

前房内给药是白内障手术中有价值的辅助手段,使外科医生能够更有效地处理常规及复杂病例。了解其正确使用方法和潜在风险对于最大限度提高患者安全性及手术成功率至关重要。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验