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锥蓝辅助下小儿白内障手术中的后囊撕开术

Trypan blue-assisted posterior capsulorhexis in pediatric cataract surgery.

作者信息

Lotfy Ayman, Abdelrahman Ayman

机构信息

Ophthalmology Department, Zagazig University Hospital; Alpha Vision Center, Zagazig, Egypt.

出版信息

Clin Ophthalmol. 2017 Jan 24;11:219-222. doi: 10.2147/OPTH.S123150. eCollection 2017.

DOI:10.2147/OPTH.S123150
PMID:28182152
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5279846/
Abstract

PURPOSE

To evaluate the safety and efficacy of staining the posterior capsule with trypan blue during capsulorhexis in pediatric cataract surgery.

PATIENTS AND METHODS

This was a prospective randomized comparative study carried out at Alpha Vision Center, Zagazig, Egypt. This study included 2 groups of children with pediatric cataract randomly allocated to undergo irrigation and aspiration. In the trypan group, which included 11 eyes, trypan blue was used to stain the posterior capsule during posterior capsulorhexis. In the control group, which included 10 eyes, no staining was performed. All surgeries were performed by the same surgeon. The 2 groups were compared for criteria such as completion of capsulorhexis, disruption of vitreous face and in-the-bag intraocular lens implantation.

RESULTS

This study included 21 eyes of 16 patients (age range: 6 months-4 years). A statistically significant difference was observed for the following parameters between the 2 groups: capsulorhexis completion (=0.04), vitreous face disruption (=0.01) and in-the-bag intraocular lens implantation (=0.022).

CONCLUSION

This study suggests that staining of the posterior capsule during capsulorhexis in pediatric cataract operation gives better results than capsulorhexis without staining. The stain changes the capsule texture making capsulorhexis easier with fewer complications.

摘要

目的

评估在儿童白内障手术撕囊过程中用台盼蓝对后囊膜进行染色的安全性和有效性。

患者与方法

这是一项在埃及扎加齐格阿尔法视觉中心进行的前瞻性随机对照研究。本研究纳入2组患有儿童白内障的患儿,随机分配接受冲洗吸出术。在台盼蓝组(11只眼)中,在撕后囊膜时使用台盼蓝对后囊膜进行染色。在对照组(10只眼)中,不进行染色。所有手术均由同一位外科医生进行。比较两组在撕囊完成情况、玻璃体前界膜破裂情况及囊袋内人工晶状体植入情况等标准方面的差异。

结果

本研究纳入16例患者的21只眼(年龄范围:6个月至4岁)。两组之间在以下参数方面观察到统计学上的显著差异:撕囊完成情况(=0.04)、玻璃体前界膜破裂情况(=0.01)及囊袋内人工晶状体植入情况(=0.022)。

结论

本研究表明,儿童白内障手术撕囊过程中对后囊膜进行染色比不染色的撕囊效果更好。染色改变了囊膜质地,使撕囊更容易且并发症更少。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4992/5279846/3ddd6bc9d17e/opth-11-219Fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4992/5279846/3ddd6bc9d17e/opth-11-219Fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4992/5279846/3ddd6bc9d17e/opth-11-219Fig1.jpg

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本文引用的文献

1
Posterior capsule management in congenital cataract surgery.先天性白内障手术中后囊膜的管理。
J Cataract Refract Surg. 2011 Jan;37(1):173-93. doi: 10.1016/j.jcrs.2010.10.036.
2
Posterior capsulorhexis combined with optic buttonholing: an alternative to standard in-the-bag implantation of sharp-edged intraocular lenses? A critical analysis of 1000 consecutive cases.后囊膜撕开联合光学部纽扣样撕裂:一种替代标准的锐边人工晶状体囊袋内植入的方法?对连续1000例病例的批判性分析
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Completion rate of primary posterior continuous curvilinear capsulorhexis and vitreous disturbance during congenital cataract surgery.
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Long-term results of trypan blue dye irrigation in the capsular bag to prevent posterior capsule opacification: A randomized trial.锥蓝染料囊袋内灌注预防后囊膜混浊的长期结果:一项随机试验。
Indian J Ophthalmol. 2017 Dec;65(12):1440-1444. doi: 10.4103/ijo.IJO_454_17.
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Efficacy of trypan blue in posterior capsulorhexis with optic capture in pediatric cataracts [ISRCTN48221688].锥蓝在小儿白内障光学捕获后囊撕开术中的疗效[国际标准随机对照试验编号:ISRCTN48221688]
BMC Ophthalmol. 2006 Mar 16;6:12. doi: 10.1186/1471-2415-6-12.
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Posterior vertical capsulotomy with optic entrapment of the intraocular lens in congenital cataracts--prevention of capsule opacification.先天性白内障后囊垂直切开联合人工晶状体视神经嵌顿术——预防囊膜混浊
J Cataract Refract Surg. 2005 May;31(5):886-94. doi: 10.1016/j.jcrs.2004.08.055.
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Surgical technique and postoperative complications in pediatric cataract surgery: retrospective analysis of 21 cases.小儿白内障手术的手术技术及术后并发症:21例回顾性分析
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Anterior and posterior capsulorhexis in pediatric cataract surgery with or without trypan blue dye: randomized prospective clinical study.小儿白内障手术中使用或不使用台盼蓝染料进行前囊和后囊连续环形撕囊:随机前瞻性临床研究
J Cataract Refract Surg. 2003 Sep;29(9):1733-7. doi: 10.1016/s0886-3350(03)00229-3.
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Role of posterior capsulotomy with vitrectomy and intraocular lens design and material in reducing posterior capsule opacification after pediatric cataract surgery.后囊切开联合玻璃体切除术以及人工晶状体设计和材料在减少儿童白内障手术后后囊混浊中的作用。
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Br J Ophthalmol. 2002 Aug;86(8):857-9. doi: 10.1136/bjo.86.8.857.
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Trypan-blue-assisted posterior capsule plaque removal.锥蓝辅助后囊膜斑块切除术。
J Cataract Refract Surg. 2002 Jun;28(6):916-7. doi: 10.1016/s0886-3350(02)01416-5.