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疟原虫裂殖子表面被膜的寄生起源的进一步证据。

Further evidence for the parasitic origin of the surface coat on Malaria merozoites.

作者信息

Mason S J, Aikawa M, Shiroishi T, Miller L H

出版信息

Am J Trop Med Hyg. 1977 Mar;26(2):195-7. doi: 10.4269/ajtmh.1977.26.195.

DOI:10.4269/ajtmh.1977.26.195
PMID:403820
Abstract

It has been observed that a surface coat, 20 nm in thickness, extends from the plasma membrane of extracellular merozoites and that this coat contains strain-specific antigens. In the present study we determined the possible effect of protein in the culture medium on this structure. The surface coat on merozoites in culture medium devoid of protein was indistinguishable by transmission electron microscopy from the coat in a protein-containing medium. This supports the hypothesis that the surface coat originates from the parasite rather than from adsorbed serum protein.

摘要

据观察,一种厚度为20纳米的表面被膜从细胞外裂殖子的质膜延伸出来,并且这种被膜含有菌株特异性抗原。在本研究中,我们确定了培养基中的蛋白质对这种结构可能产生的影响。在不含蛋白质的培养基中培养的裂殖子上的表面被膜,通过透射电子显微镜观察,与含蛋白质培养基中的被膜没有区别。这支持了表面被膜起源于寄生虫而非吸附的血清蛋白这一假说。

相似文献

1
Further evidence for the parasitic origin of the surface coat on Malaria merozoites.疟原虫裂殖子表面被膜的寄生起源的进一步证据。
Am J Trop Med Hyg. 1977 Mar;26(2):195-7. doi: 10.4269/ajtmh.1977.26.195.
2
Malaria (Plasmodium knowlesi) merozoites: immunity and the surface coat.疟疾(诺氏疟原虫)裂殖子:免疫与表面被膜
J Immunol. 1975 Apr;114(4):1237-42.
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Structure and development of the surface coat of erythrocytic merozoites of Plasmodium knowlesi.诺氏疟原虫红细胞内期裂殖子表面被膜的结构与发育
Cell Tissue Res. 1986;245(2):281-90. doi: 10.1007/BF00213933.
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Erythrocyte entry by malarial parasites. A moving junction between erythrocyte and parasite.疟原虫进入红细胞。红细胞与寄生虫之间的移动连接。
J Cell Biol. 1978 Apr;77(1):72-82. doi: 10.1083/jcb.77.1.72.
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Lamellar membranes associated with rhoptries in erythrocytic merozoites of Plasmodium knowlesi: a clue to the mechanism of invasion.诺氏疟原虫红细胞内期裂殖子中与棒状体相关的板层膜:入侵机制的线索
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Invasion of erythrocytes by malaria merozoites.疟原虫裂殖子侵入红细胞。
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Monoclonal antibodies to a 140,000-m.w. protein on Plasmodium knowlesi merozoites inhibit their invasion of rhesus erythrocytes.针对诺氏疟原虫裂殖子上一种分子量为140,000的蛋白质的单克隆抗体可抑制其对恒河猴红细胞的侵袭。
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A freeze-fracture study on the parasite-erythrocyte interrelationship in Plasmodium knowlesi infections.诺氏疟原虫感染中寄生虫与红细胞相互关系的冷冻蚀刻研究。
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引用本文的文献

1
Structure and development of the surface coat of erythrocytic merozoites of Plasmodium knowlesi.诺氏疟原虫红细胞内期裂殖子表面被膜的结构与发育
Cell Tissue Res. 1986;245(2):281-90. doi: 10.1007/BF00213933.
2
Role of the surface coat in in vitro attachment and phagocytosis of Plasmodium berghei by peritoneal macrophages.表面被膜在伯氏疟原虫被腹膜巨噬细胞体外黏附和吞噬过程中的作用
Infect Immun. 1978 Jun;20(3):827-35. doi: 10.1128/iai.20.3.827-835.1978.