Brooks C, Kreier J P
Infect Immun. 1978 Jun;20(3):827-35. doi: 10.1128/iai.20.3.827-835.1978.
Evidence is presented to indicate that Plasmodium berghei merozoites, but not trophozotites, have an antiphagocytic capsule. The capsule appears to form around the developing merozoties of the schizont in the parasitophorous vacuole. Serum from animals immune to P. berghei reacts with this capsule. After reaction with immune serum, the antiphagocytic action of the capsule is lost. By the process of binding serum protein, the capsule becomes electron dense and can be readily visuallzed as the surface coat by electron microscopy. At physiological temperatures, phagocytosis by macrophages rapidly follows adhesion of antibody-coated parasites. Both tight and loose phagosomes are formed.
有证据表明，伯氏疟原虫裂殖子有抗吞噬囊膜，而滋养体没有。该囊膜似乎在寄生泡内裂殖体发育中的裂殖子周围形成。对伯氏疟原虫免疫的动物血清会与这种囊膜发生反应。与免疫血清反应后，囊膜的抗吞噬作用丧失。通过结合血清蛋白的过程，囊膜变得电子致密，通过电子显微镜可轻易将其视为表面被膜。在生理温度下，巨噬细胞的吞噬作用会在抗体包被的寄生虫黏附后迅速发生。会形成紧密和松散的吞噬体。
