诺氏疟原虫感染中寄生虫与红细胞相互关系的冷冻蚀刻研究。
A freeze-fracture study on the parasite-erythrocyte interrelationship in Plasmodium knowlesi infections.
作者信息
McLaren D J, Bannister L H, Trigg P I, Butcher G A
出版信息
Bull World Health Organ. 1977;55(2-3):199-203.
Abstract
Freeze-fracture studies were made on the parasite and the erythrocyte in P. knowlesi infections. There is a loss of transmembrane integral proteins from the plasma membrane of the schizont-infected erythrocyte and the intraerythrocytic parasite synthesizes new transmembrane proteins as development proceeds. Formation of the parasitophorous vacuole includes changes in the number of integral proteins present in the vacuolar membrane, indicating that this membrane may be modified by and in part derived from the parasite.
摘要
对诺氏疟原虫感染中的寄生虫和红细胞进行了冷冻蚀刻研究。裂殖体感染的红细胞质膜上的跨膜整合蛋白会丢失，并且随着发育的进行，红细胞内的寄生虫会合成新的跨膜蛋白。寄生泡的形成包括泡膜中存在的整合蛋白数量的变化，这表明该膜可能会被寄生虫修饰并部分源自寄生虫。
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