Wang Han, Li Xinzhi, Li Bo, Zhang Qiong, Que Xiangyong, Chen Wenyao, Huang Chongyu, Ai Qinyue, Abulimiti Mireadeli, Yang Qi, Zhang Lunci
Three Gorges University Renhe Hospital, Yichang, China.
China Three Gorges University, Yichang, China.
Eur Spine J. 2025 May 17. doi: 10.1007/s00586-025-08849-2.
Gout is a metabolic disorder caused by the deposition of urate crystals in the joints and surrounding tissues. Prolonged hyperuricemia leads to the formation and accumulation of urate crystals, often resulting in acute and chronic joint damage. Spinal gout is a rare type caused by the deposition of urate crystals in spinal tissues. It leads to local inflammation, pain, and, in severe cases, neurological symptoms. The clinical presentation of spinal gout is varied and lacks specificity, making it easily confused with other spinal disorders, especially in elderly patients.
We report six rare lumbar disc deposits caused by tophi (gout stones). The main symptoms in these patients were lower back pain accompanied by leg pain and/or numbness. All patients underwent surgical treatment with satisfactory outcomes. We also provide a brief review of the relevant literature on spinal gout.
This article discusses the pathophysiological mechanisms, clinical manifestations, imaging characteristics, diagnosis, and treatment strategies for spinal gout. The goal is to enhance clinicians' awareness of spinal gout, and enable early detection, diagnosis, and treatment.
痛风是一种代谢紊乱疾病，由尿酸盐结晶在关节及周围组织沉积所致。长期高尿酸血症会导致尿酸盐结晶的形成与积聚，常引发急慢性关节损伤。脊柱痛风是一种罕见类型，由尿酸盐结晶在脊柱组织沉积引起。它会导致局部炎症、疼痛，严重时还会出现神经症状。脊柱痛风的临床表现多样且缺乏特异性，这使其容易与其他脊柱疾病混淆，尤其是在老年患者中。
我们报告了6例由痛风石（痛风结节）引起的罕见腰椎间盘沉积物病例。这些患者的主要症状为下背部疼痛并伴有腿部疼痛和/或麻木。所有患者均接受了手术治疗，效果满意。我们还对脊柱痛风的相关文献进行了简要综述。
本文探讨了脊柱痛风的病理生理机制、临床表现、影像学特征、诊断及治疗策略。目的是提高临床医生对脊柱痛风的认识，实现早期发现、诊断和治疗。
