Barbu Laurenţiu Augustus, Vasile Liviu, Ţenea-Cojan Tiberiu Ştefăniţă, Mogoş Gabriel Florin Răzvan, Şurlin Valeriu, Vîlcea Ionică Daniel, Cercelaru Liliana, Mogoantă Stelian Ştefăniţă, Mărgăritescu Nicolae Dragoş
Department of Surgery, University of Medicine and Pharmacy of Craiova, Romania;
Rom J Morphol Embryol. 2025 Jan-Mar;66(1):39-49. doi: 10.47162/RJME.66.1.03.
BACKGROUND/OBJECTIVES: Ovarian neoplasms are the third most common gynecological cancer and carry a poorer prognosis than breast cancer. Endometrioid borderline ovarian tumors (EBOTs) are intermediate epithelial lesions, histologically showing glandular patterns with mild to moderate atypia and no stromal invasion. Study selection for review: A comprehensive electronic search was conducted on PubMed to identify risk factors and etiological determinants associated with ovarian endometrioid adenofibroma (EA).
A 27-year-old woman with a left ovarian cyst underwent a laparoscopic procedure to remove the adnexa after imaging showed a 6 cm mass. Surgery was successful, and she was discharged without complications.
This study highlights the diagnostic challenges of EBOTs, the essential role of immunohistochemistry, and the need for careful surgical and fertility-preserving strategies. It also draws attention to possible risks linked to fertility treatments. Fertility preservation is crucial in young patients, favoring uterine and ovarian conservation. In early-stage, small, non-invasive tumors, laparoscopy is the preferred approach. EAs are uncommon benign ovarian tumors, accounting for approximately 1% of epithelial neoplasms, and are predominantly unilateral.
背景/目的：卵巢肿瘤是第三常见的妇科癌症，预后比乳腺癌差。子宫内膜样交界性卵巢肿瘤（EBOTs）是中间型上皮性病变，组织学上表现为具有轻度至中度异型性且无间质浸润的腺管模式。综述的研究选择：在PubMed上进行了全面的电子检索，以确定与卵巢子宫内膜样腺纤维瘤（EA）相关的危险因素和病因决定因素。
一名27岁患有左侧卵巢囊肿的女性，在影像学检查显示有一个6厘米的肿块后，接受了腹腔镜手术切除附件。手术成功，她出院时无并发症。
本研究强调了EBOTs的诊断挑战、免疫组织化学的重要作用以及谨慎的手术和保留生育功能策略的必要性。它还提请注意与生育治疗相关的可能风险。保留生育功能对年轻患者至关重要，有利于保留子宫和卵巢。对于早期、小的、非侵袭性肿瘤，腹腔镜检查是首选方法。EA是罕见的卵巢良性肿瘤，约占上皮性肿瘤的1%，且主要为单侧性。
