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一例有化疗及异基因外周血干细胞移植史的多发性小汗腺汗孔瘤病例

A Case of Multiple Eccrine Poromas with a History of Chemotherapy and Allogeneic Peripheral Blood Stem Cell Transplantation.

作者信息

Yoshiike Haruna, Kawai Kenichiro, Nishimoto Soh, Ide Yoshihiro, Tamaki Hiroya, Kakibuchi Masao

机构信息

Department of Plastic Surgery, Hyogo Medical University, Hyogo, Japan.

Department of Surgical Pathology, Hyogo Medical University, Hyogo, Japan.

出版信息

J Plast Reconstr Surg. 2023 Mar 15;2(4):142-146. doi: 10.53045/jprs.2022-0023. eCollection 2023 Oct 27.

Abstract

A "poroid cell neoplasm" is a general term used to describe nodular tumors that consist of poroid cells and cuticular cells. Eccrine poroma, the most common type of poroid cell neolplasm, is a tumor continuous with the epidermis and extends into the dermis in a cord-like fashion. This tumor is almost always seen as a single lesion, with cases of multiple eccrine poromas (eccrine poromatosis) being exceedingly rare. In fact, there have only been about 20 reported cases of multiple eccrine poromas worldwide; all of which were associated with some immunosuppressive state. Here we report another case of eccrine poromatosis; this time in a patient who received an allogeneic peripheral blood stem cell transplant for acute lymphocytic leukemia 18 years prior. Our case of eccrine pormatosis is particularly rare that it involved a truncal tumor distribution, whereas the other reported cases were generally isolated to the extremities.

摘要

“类汗孔瘤细胞肿瘤”是一个通用术语,用于描述由类汗孔瘤细胞和角质形成细胞组成的结节状肿瘤。小汗腺汗孔瘤是类汗孔瘤细胞肿瘤最常见的类型,是一种与表皮相连并以条索状方式延伸至真皮的肿瘤。这种肿瘤几乎总是表现为单个病变,多发型小汗腺汗孔瘤(汗孔瘤病)的病例极为罕见。事实上,全球仅报道过约20例多发型小汗腺汗孔瘤病例;所有这些病例都与某种免疫抑制状态有关。在此,我们报告另一例汗孔瘤病病例;此次患者18年前因急性淋巴细胞白血病接受了异基因外周血干细胞移植。我们的汗孔瘤病病例尤为罕见,因为肿瘤分布于躯干,而其他报道的病例通常局限于四肢。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/56e5/12078117/329d003411ef/jprs-02-04-0142-g001.jpg

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