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面神经管原发性副神经节瘤1例罕见病例

A Rare Case of Primary Paraganglioma of the Facial Nerve Canal.

作者信息

Claeys Simon, Dhooge Ingeborg, Van Driessche Veroniek

机构信息

Ghent University Hospital, Ghent, Belgium.

出版信息

J Belg Soc Radiol. 2025 May 13;109(1):20. doi: 10.5334/jbsr.3957. eCollection 2025.

DOI:10.5334/jbsr.3957
PMID:40385691
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12082460/
Abstract

We report the case of a 54‑year‑old woman with 3‑year‑history of right facial paralysis. Computed tomography (CT) and magnetic resonance imaging (MRI) findings were highly suggestive of a primary paraganglioma (PGL) of the facial nerve canal (FNC). Ga‑DOTATATE positron emission tomography (PET)/CT confirmed the neuroendocrine nature of the tumor. The combined imaging findings of permeative bone destruction, rapid wash‑in and wash‑out perfusion, and Ga‑DOTATATE tracer uptake in a lesion arising from the mastoid segment of the FNC are diagnostic of a primary PGL of the FNC and may obviate the need for histological confirmation.

摘要

我们报告了一例54岁女性,有3年右侧面部麻痹病史。计算机断层扫描(CT)和磁共振成像(MRI)结果高度提示面神经管(FNC)原发性副神经节瘤(PGL)。镓[Ga]‑DOTATATE正电子发射断层扫描(PET)/CT证实了肿瘤的神经内分泌性质。FNC乳突段病变出现的渗透性骨质破坏、快速流入和流出灌注以及镓[Ga]‑DOTATATE示踪剂摄取的综合影像学表现可诊断为FNC原发性PGL,可能无需组织学证实。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8bfe/12082460/1370a7c5875e/jbsr-109-1-3957-g3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8bfe/12082460/42a8bc1a599a/jbsr-109-1-3957-g1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8bfe/12082460/74df6c9884ac/jbsr-109-1-3957-g2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8bfe/12082460/1370a7c5875e/jbsr-109-1-3957-g3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8bfe/12082460/42a8bc1a599a/jbsr-109-1-3957-g1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8bfe/12082460/74df6c9884ac/jbsr-109-1-3957-g2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8bfe/12082460/1370a7c5875e/jbsr-109-1-3957-g3.jpg

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本文引用的文献

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Natural history of facial paraganglioma with 2 decades of follow-up: A case report and literature review.
Am J Otolaryngol. 2023 Sep-Oct;44(5):103952. doi: 10.1016/j.amjoto.2023.103952. Epub 2023 Jun 8.
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Head and Neck Paragangliomas: An Update on the Molecular Classification, State-of-the-Art Imaging, and Management Recommendations.头颈部副神经节瘤:分子分类、最新成像技术和管理建议的更新。
Radiol Imaging Cancer. 2022 May;4(3):e210088. doi: 10.1148/rycan.210088.
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Primary Paraganglioma of the Facial Canal: An Evidence-Based Approach.面神经管内副节瘤:一种基于证据的方法。
Otolaryngol Head Neck Surg. 2020 Apr;162(4):458-468. doi: 10.1177/0194599820907303. Epub 2020 Feb 25.
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The glomus jugulare, a nonchromaffin paraganglion, in man.人颈静脉球,一种非嗜铬副神经节。
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