• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

旋转皮瓣联合切开负压伤口治疗糖尿病足底溃疡的疗效

Outcome of Rotation Flap Combined with Incisional Negative Pressure Wound Therapy for Plantar Diabetic Foot Ulcers.

作者信息

Feng Jiajun, Thng Coeway Boulder, Wong Jason, Alison Quah Mei Fern, Lim Nicole Tao Ying, Wong Francis Keng Lin, Leow Kimberley, Alvis Leon Timothy Charles, Leong Sum, Irani Farah Gillan, Png Wenxian, Cher Eric Wei Liang, Kok Yee Onn, Wong Allen Wei-Jiat, Chew Khong Yik

机构信息

Department of Plastic, Reconstructive, and Aesthetic Surgery, Sengkang General Hospital, Singapore, Singapore.

Department of Plastic Surgery and Burns, University Hospital of South Manchester, England.

出版信息

Arch Plast Surg. 2025 May 15;52(3):169-177. doi: 10.1055/a-2544-2938. eCollection 2025 May.

DOI:10.1055/a-2544-2938
PMID:40386003
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12081091/
Abstract

Diabetic foot ulcers (DFUs) affect approximately 20% of diabetic patients and pose significant risks, especially for plantar wounds that bear weight. Conventional treatments often have suboptimal results, necessitating the exploration of reconstructive options. Plastic surgery interventions, such as skin grafts and flaps, have shown promising outcomes, but with considerable complications. This study evaluates the efficacy of rotation flap reconstruction with incisional negative pressure wound therapy (NPWT) for plantar DFUs.  We conducted a retrospective review of 42 patients who underwent rotation flap closure for plantar DFUs. We optimized the preoperative conditions with aggressive infection control and vascular assessment. We performed rotation flaps with incisional NPWT as the operative technique. We managed the postoperative conditions with offloading continuous incisional NPWT and footwear.  All patients achieved initial wound healing, with a median duration of 36 days. Complications occurred in 14% of cases. The recurrence rate was 21% during follow-up, which was significantly higher in patients with Charcot foot deformity. We present three illustrative cases that demonstrate the efficacy of rotation flaps.  Rotation flap closure, supplemented by incisional NPWT, emerges as a viable option for plantar DFUs, achieving high initial healing rates, low complications, and reduced recurrence. Notably, patients with Charcot foot deformity require more attention and intervention to prevent recurrence.

摘要

糖尿病足溃疡(DFUs)影响约20%的糖尿病患者,并带来重大风险,尤其是对于承受体重的足底伤口。传统治疗往往效果欠佳,因此有必要探索重建治疗方案。整形手术干预措施,如皮肤移植和皮瓣移植,已显示出有前景的效果,但并发症较多。本研究评估采用切开负压伤口治疗(NPWT)的旋转皮瓣重建术治疗足底DFUs的疗效。

我们对42例行旋转皮瓣闭合术治疗足底DFUs的患者进行了回顾性研究。我们通过积极的感染控制和血管评估来优化术前条件。我们采用切开NPWT的旋转皮瓣作为手术技术。我们通过持续切开NPWT减压和使用合适的鞋具来处理术后情况。

所有患者均实现了伤口初期愈合,中位愈合时间为36天。14%的病例出现了并发症。随访期间复发率为21%,夏科氏足畸形患者的复发率显著更高。我们展示了三个说明性病例,以证明旋转皮瓣的疗效。

切开NPWT辅助的旋转皮瓣闭合术是治疗足底DFUs的一种可行选择,可实现较高的初期愈合率、较低的并发症发生率和较低的复发率。值得注意的是,夏科氏足畸形患者需要更多关注和干预以预防复发。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3622/12081091/3c72231af4f0/10-1055-a-2544-2938-i24mar0042oa-1s.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3622/12081091/d79b451888e1/10-1055-a-2544-2938-i24mar0042oa-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3622/12081091/fbbf22c3e2c8/10-1055-a-2544-2938-i24mar0042oa-2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3622/12081091/448494c9a267/10-1055-a-2544-2938-i24mar0042oa-3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3622/12081091/698c7b3d2f36/10-1055-a-2544-2938-i24mar0042oa-4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3622/12081091/cc681fdbde75/10-1055-a-2544-2938-i24mar0042oa-5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3622/12081091/3c72231af4f0/10-1055-a-2544-2938-i24mar0042oa-1s.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3622/12081091/d79b451888e1/10-1055-a-2544-2938-i24mar0042oa-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3622/12081091/fbbf22c3e2c8/10-1055-a-2544-2938-i24mar0042oa-2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3622/12081091/448494c9a267/10-1055-a-2544-2938-i24mar0042oa-3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3622/12081091/698c7b3d2f36/10-1055-a-2544-2938-i24mar0042oa-4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3622/12081091/cc681fdbde75/10-1055-a-2544-2938-i24mar0042oa-5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3622/12081091/3c72231af4f0/10-1055-a-2544-2938-i24mar0042oa-1s.jpg

相似文献

1
Outcome of Rotation Flap Combined with Incisional Negative Pressure Wound Therapy for Plantar Diabetic Foot Ulcers.旋转皮瓣联合切开负压伤口治疗糖尿病足底溃疡的疗效
Arch Plast Surg. 2025 May 15;52(3):169-177. doi: 10.1055/a-2544-2938. eCollection 2025 May.
2
Flap monitoring with incisional negative pressure wound therapy (NPWT) in diabetic foot patients.切口负压伤口治疗(NPWT)下的糖尿病足患者皮瓣监测。
Sci Rep. 2022 Sep 20;12(1):15684. doi: 10.1038/s41598-022-20088-9.
3
Ostectomy and Medial Plantar Artery Flap Reconstruction for Charcot Foot Ulceration Involving the Midfoot.中足Charcot足溃疡的截骨术及足底内侧动脉皮瓣重建术
J Foot Ankle Surg. 2016 May-Jun;55(3):628-32. doi: 10.1053/j.jfas.2015.05.005. Epub 2015 Jul 16.
4
[Application of free anterolateral thigh flap with fascia lata for diabetic foot ulcers with bone exposure].带阔筋膜的股前外侧游离皮瓣在伴有骨质外露的糖尿病足溃疡中的应用
Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2022 Jan 15;36(1):86-91. doi: 10.7507/1002-1892.202108110.
5
A Novel Approach to Limb Salvage: Healing Transmetatarsal Amputations without a Viable Plantar Flap.一种新的保肢方法:无需可行的足底皮瓣即可治愈跖骨间截肢。
Ann Vasc Surg. 2021 Jan;70:51-55. doi: 10.1016/j.avsg.2020.08.098. Epub 2020 Aug 29.
6
A Meta-Analysis of the Outcomes of Metatarsal Head Resection for the Treatment of Neuropathic Diabetic Foot Ulcers.跖骨头切除术治疗糖尿病神经病变性足部溃疡疗效的Meta分析
Adv Wound Care (New Rochelle). 2021 Feb;10(2):81-90. doi: 10.1089/wound.2020.1261. Epub 2020 Sep 29.
7
The Efficacy of Negative Pressure Wound Therapy (NPWT) on Healing of Diabetic Foot Ulcers: A Literature Review.负压伤口治疗(NPWT)对糖尿病足溃疡愈合的疗效:一项文献综述
Curr Diabetes Rev. 2024;20(8):1-11. doi: 10.2174/0115733998229877230926073555.
8
Footwear and offloading interventions to prevent and heal foot ulcers and reduce plantar pressure in patients with diabetes: a systematic review. footwear and offloading interventions to prevent and heal foot ulcers and reduce plantar pressure in patients with diabetes: a systematic review.
Diabetes Metab Res Rev. 2016 Jan;32 Suppl 1:99-118. doi: 10.1002/dmrr.2702.
9
Use of negative pressure wound therapy on locoregional flaps: a case-control study.负压伤口疗法在局部皮瓣中的应用:一项病例对照研究。
J Wound Care. 2023 Apr 1;32(Sup4):S5-S13. doi: 10.12968/jowc.2023.32.Sup4.S5.
10
A mouldable fibreglass backslab device as a novel approach to offload chronic plantar foot ulcers: A retrospective observational audit.一种可塑形的玻璃纤维背板装置作为一种新颖的方法来减轻慢性足底溃疡:回顾性观察性审计。
J Foot Ankle Res. 2024 Sep;17(3):e70001. doi: 10.1002/jfa2.70001.

本文引用的文献

1
Influence of Closed-incision Negative Pressure Wound Therapy on Abdominal Site Complications in Autologous Breast Reconstruction.闭合切口负压伤口治疗对自体乳房重建腹部部位并发症的影响。
Plast Reconstr Surg Glob Open. 2023 Oct 9;11(10):e5326. doi: 10.1097/GOX.0000000000005326. eCollection 2023 Oct.
2
Use of negative pressure wound therapy on locoregional flaps: a case-control study.负压伤口疗法在局部皮瓣中的应用:一项病例对照研究。
J Wound Care. 2023 Apr 1;32(Sup4):S5-S13. doi: 10.12968/jowc.2023.32.Sup4.S5.
3
Negative pressure wound therapy compared with conventional wound dressings for closed incisions in orthopaedic trauma surgery: A meta-analysis.
负压伤口疗法与传统伤口敷料在骨科创伤手术闭合切口的比较:一项荟萃分析。
Int Wound J. 2022 Oct;19(6):1319-1328. doi: 10.1111/iwj.13726. Epub 2021 Dec 2.
4
Diabetic Wound-Healing Science.糖尿病创面愈合科学。
Medicina (Kaunas). 2021 Oct 8;57(10):1072. doi: 10.3390/medicina57101072.
5
Outcomes and prognosis of diabetic foot ulcers treated by an interdisciplinary team in Canada.加拿大跨学科团队治疗糖尿病足溃疡的结果和预后。
Int Wound J. 2021 Apr;18(2):134-146. doi: 10.1111/iwj.13505. Epub 2020 Nov 25.
6
Recurrence rates suggest delayed identification of plantar ulceration for patients in diabetic foot remission.复发率表明,糖尿病足缓解患者的足底溃疡识别存在延迟。
BMJ Open Diabetes Res Care. 2020 Sep;8(1). doi: 10.1136/bmjdrc-2020-001697.
7
Five year mortality and direct costs of care for people with diabetic foot complications are comparable to cancer.糖尿病足并发症患者的 5 年死亡率和医疗费用直接堪比癌症。
J Foot Ankle Res. 2020 Mar 24;13(1):16. doi: 10.1186/s13047-020-00383-2.
8
Negative pressure wound therapy with instillation: International consensus guidelines update.负压伤口治疗联合灌洗:国际共识指南更新。
Int Wound J. 2020 Feb;17(1):174-186. doi: 10.1111/iwj.13254. Epub 2019 Oct 30.
9
Algorithm for Free Perforator Flap Selection in Lower Extremity Reconstruction Based on 563 Cases.基于 563 例的下肢重建中游离穿支皮瓣选择的算法。
Plast Reconstr Surg. 2019 Nov;144(5):1202-1213. doi: 10.1097/PRS.0000000000006167.
10
Editor's Choice - Diabetic Limb Salvage With Endovascular Revascularisation and Free Tissue Transfer: Long-Term Follow up.编辑精选 - 血管内血运重建和游离组织移植治疗糖尿病肢体缺血的保肢效果:长期随访结果。
Eur J Vasc Endovasc Surg. 2019 Apr;57(4):527-536. doi: 10.1016/j.ejvs.2018.11.010. Epub 2019 Mar 23.