Kennedy Kanak V, Fawad Jibraan A, Neugut Y Dana, Valenzuela-Araujo Doris, Coe Alexander, Bhatti Tricia R, Acord Michael, Manfredi Michael D, Mamula Petar, Loomes Kathleen M, Brownell Jefferson N
Division of Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics Children's Hospital of Philadelphia Philadelphia Pennsylvania USA.
Division of Pediatric Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics Stanford University School of Medicine Palo Alto California USA.
JPGN Rep. 2025 Feb 25;6(2):189-192. doi: 10.1002/jpr3.70003. eCollection 2025 May.
Pediatric upper gastrointestinal (GI) bleeding secondary to duodenal ulceration is a potentially serious and life-threatening condition with a broad differential diagnosis. We present a pediatric case of a pancreatic head solid pseudopapillary neoplasm (SPN) presenting with duodenal ulceration and recurrent upper GI bleeding. This case highlights pancreatic SPNs as a rare extrinsic cause of duodenal ulceration. Recurrence and progression in size and extent of a duodenal ulceration in the absence of other inciting factors should raise suspicion for an extraluminal etiology.
小儿十二指肠溃疡继发上消化道(GI)出血是一种潜在严重且危及生命的疾病,鉴别诊断范围广泛。我们报告一例小儿胰头实性假乳头状瘤(SPN),表现为十二指肠溃疡和反复上消化道出血。该病例凸显了胰腺SPN作为十二指肠溃疡罕见的外在病因。在没有其他诱发因素的情况下,十二指肠溃疡复发且大小和范围进展,应怀疑存在腔外病因。