卡莫司汀、环磷酰胺联合阿霉素多药化疗治疗晚期卵巢癌。
Polychemotherapy with carmustine, cyclophosphamide plus adriamycin in the treatment of advanced ovarian cancer.
作者信息
Facchini V, Gadducci A, Bogi G, Colombi L, Basile A G, Ballantini M, De Pasquale F, Fioretti P
出版信息
Eur J Gynaecol Oncol. 1985;6(1):37-40.
The Authors describe their experience with a combination therapy with carmustine (BCNU), cyclophosphamide (CTX) plus adriamycin (ADM) in the treatment of advanced ovarian cancer. The complete remission was obtained in 33.3% of subjects, the partial remission in 37.5%. Almost all patients suffered nausea, vomiting and alopecia. Myelosuppression was acceptable. No heart damage was observed. This pharmacological association can be considered an effective medical treatment in the management of ovarian carcinomas in advanced stages.
作者描述了他们使用卡莫司汀（BCNU）、环磷酰胺（CTX）联合阿霉素（ADM）的联合疗法治疗晚期卵巢癌的经验。33.3%的受试者获得完全缓解，37.5%获得部分缓解。几乎所有患者都出现恶心、呕吐和脱发。骨髓抑制可以接受。未观察到心脏损伤。这种药物联合可被认为是晚期卵巢癌治疗中的一种有效医学疗法。
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