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Antibiotics for suspected sepsis: who and when?

作者信息

Klompas Michael, Lapão Luís Velez, Taylor Stephanie Parks

机构信息

Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, USA.

Department of Medicine, Brigham and Women's Hospital, Boston, USA.

出版信息

Intensive Care Med. 2025 May 19. doi: 10.1007/s00134-025-07940-y.

DOI:10.1007/s00134-025-07940-y
PMID:40387882
Abstract
摘要

相似文献

1
Antibiotics for suspected sepsis: who and when?用于疑似脓毒症的抗生素:哪些人以及何时使用?
Intensive Care Med. 2025 May 19. doi: 10.1007/s00134-025-07940-y.
2
Granulocyte transfusions for neonates with confirmed or suspected sepsis and neutropaenia.对确诊或疑似败血症及中性粒细胞减少症的新生儿进行粒细胞输注。
Cochrane Database Syst Rev. 2003(4):CD003956. doi: 10.1002/14651858.CD003956.
3
Procalcitonin testing to guide antibiotic therapy for the treatment of sepsis in intensive care settings and for suspected bacterial infection in emergency department settings: a systematic review and cost-effectiveness analysis.降钙素原检测用于指导重症监护环境中脓毒症治疗及急诊科环境中疑似细菌感染治疗的抗生素疗法:一项系统评价与成本效益分析
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4
Automated monitoring compared to standard care for the early detection of sepsis in critically ill patients.与标准护理相比,自动监测用于危重症患者脓毒症的早期检测
Cochrane Database Syst Rev. 2018 Jun 25;6(6):CD012404. doi: 10.1002/14651858.CD012404.pub2.
5
Antibiotic regimens for suspected late onset sepsis in newborn infants.新生儿疑似晚发型败血症的抗生素治疗方案。
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G-CSF and GM-CSF for treating or preventing neonatal infections.用于治疗或预防新生儿感染的粒细胞集落刺激因子和粒细胞-巨噬细胞集落刺激因子。
Cochrane Database Syst Rev. 2003;2003(3):CD003066. doi: 10.1002/14651858.CD003066.
7
Granulocyte transfusions for neonates with confirmed or suspected sepsis and neutropenia.对确诊或疑似败血症及中性粒细胞减少症的新生儿进行粒细胞输注。
Cochrane Database Syst Rev. 2011 Oct 5;2011(10):CD003956. doi: 10.1002/14651858.CD003956.pub2.
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Antibiotics and antiseptics for venous leg ulcers.用于下肢静脉溃疡的抗生素和防腐剂
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Prehospital antibiotics and intravenous fluids for patients with sepsis: protocol for a 2×2 factorial randomised controlled trial.脓毒症患者的院前抗生素和静脉输液治疗:一项2×2析因随机对照试验方案
BMJ Open. 2025 May 27;15(5):e104257. doi: 10.1136/bmjopen-2025-104257.
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Epidemiology and Outcomes of Antibiotic De-escalation in Patients With Suspected Sepsis in US Hospitals.美国医院疑似脓毒症患者抗生素降阶梯治疗的流行病学及治疗结果
Clin Infect Dis. 2025 Feb 5;80(1):108-117. doi: 10.1093/cid/ciae591.

本文引用的文献

1
Decision analysis model of rapid versus deferred antibiotic initiation in patients with suspected sepsis in the emergency department.急诊科疑似脓毒症患者快速与延迟使用抗生素起始治疗的决策分析模型
Intensive Care Med. 2025 Apr 29. doi: 10.1007/s00134-025-07899-w.
2
Frequency of Antibiotic Overtreatment and Associated Harms in Patients Presenting With Suspected Sepsis to the Emergency Department: A Retrospective Cohort Study.急诊科疑似脓毒症患者抗生素过度治疗的频率及相关危害:一项回顾性队列研究
Clin Infect Dis. 2025 Jul 18;80(6):1197-1207. doi: 10.1093/cid/ciaf118.
3
Complex Sepsis Presentations, SEP-1 Compliance, and Outcomes.
复杂脓毒症表现、SEP-1依从性及预后
JAMA Netw Open. 2025 Mar 3;8(3):e251100. doi: 10.1001/jamanetworkopen.2025.1100.
4
Effect of the 1-h bundle on mortality in patients with suspected sepsis in the emergency department: a stepped wedge cluster randomized clinical trial.1 小时束带对急诊科疑似脓毒症患者死亡率的影响:一项 stepped wedge 集群随机临床试验。
Intensive Care Med. 2024 Jul;50(7):1086-1095. doi: 10.1007/s00134-024-07509-1. Epub 2024 Jun 24.
5
Improving Sepsis Outcomes in the Era of Pay-for-Performance and Electronic Quality Measures: A Joint IDSA/ACEP/PIDS/SHEA/SHM/SIDP Position Paper.在按绩效付费和电子质量措施时代提高脓毒症治疗效果:IDSA/ACEP/PIDS/SHEA/SHM/SIDP 联合立场文件。
Clin Infect Dis. 2024 Mar 20;78(3):505-513. doi: 10.1093/cid/ciad447.
6
Risk of Misleading Conclusions in Observational Studies of Time-to-Antibiotics and Mortality in Suspected Sepsis.疑似脓毒症患者抗生素使用时间与死亡率的观察性研究中存在误导结论的风险。
Clin Infect Dis. 2023 Nov 30;77(11):1534-1543. doi: 10.1093/cid/ciad450.
7
Concordance Between Initial Presumptive and Final Adjudicated Diagnoses of Infection Among Patients Meeting Sepsis-3 Criteria in the Emergency Department.急诊符合 Sepsis-3 标准的感染患者初始疑似诊断与最终确定诊断的一致性。
Clin Infect Dis. 2023 Jun 16;76(12):2047-2055. doi: 10.1093/cid/ciad101.
8
Likelihood of Bacterial Infection in Patients Treated With Broad-Spectrum IV Antibiotics in the Emergency Department.急诊使用广谱静脉抗生素治疗的患者发生细菌感染的可能性。
Crit Care Med. 2021 Nov 1;49(11):e1144-e1150. doi: 10.1097/CCM.0000000000005090.
9
A Critical Analysis of the Literature on Time-to-Antibiotics in Suspected Sepsis.疑似脓毒症抗生素使用时机文献的批判性分析
J Infect Dis. 2020 Jul 21;222(Suppl 2):S110-S118. doi: 10.1093/infdis/jiaa146.
10
Trends in False-Positive Code Sepsis Activations in the Emergency Department.急诊科假阳性脓毒症编码激活的趋势
Ann Am Thorac Soc. 2020 Apr;17(4):520-522. doi: 10.1513/AnnalsATS.201910-757RL.