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探索精神疾病患者的非医学处方:一项范围综述

Exploring non-medical prescribing for patients with mental illness: a scoping review.

作者信息

Alsaeed Bashayr A, Hall Jason, Keers Richard N

机构信息

Division of Pharmacy and Optometry, School of Health Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, The University of Manchester, Manchester, UK.

Department of Clinical Pharmacy, College of Pharmacy, Jouf University, Al-Jouf, Sakaka, 72341, Saudi Arabia.

出版信息

BMC Psychiatry. 2025 May 19;25(1):504. doi: 10.1186/s12888-025-06938-6.

Abstract

BACKGROUND

Non-medical prescribing (NMP) qualifications extend prescribing authority to nurses, pharmacists, and other allied health professionals and are advocated as a means to help improve healthcare efficiency and access to services. However, despite non-medical prescribers (NMPs) being utilised in some countries for more than two decades, less is known about their role and impact in the mental health context. This scoping review therefore aims to map published research evidence concerning NMP for patients with mental illness.

METHODS

Five electronic databases were searched from January 2003 to July 2024. Reference lists of identified papers were also checked for relevant studies. Full text primary research studies exploring the nature, impact, and implementation of NMP services for patients with mental illness and dementia in community settings were included.

RESULTS

From 22,547 retrieved papers, 63 studies were included. Of these, 57 (90.4%) detailed the nature (including the service or team they were based in, medicines prescribed, and main role(s)) of NMPs, 45 (71.4%) assessed the impact of services, and 16 (25.3%) explored factors influencing service implementation and delivery. The majority of studies originated from the USA (30/63, 47.6%), or the United Kingdom (27/63, 42.8%). Either nurse (44/63, 69.8%), pharmacist (16/63, 25.3%) or non-medical prescribing models featuring both professionals were exclusively studied (3/63, 4.7%). In the UK and USA, antidepressants (60%, 54.5%) were the most prescribed by NMPs. Although the conditions of patients managed by both nurse and pharmacist prescribers were reported to be well managed based on clinical outcomes (3/24, 12.5% and 3/13, 23%, respectively), few studies evaluated health outcomes. Training-related barriers to service delivery were commonly mentioned in UK studies (4/9, 44.4%), with financial issues reported in the USA (2/4, 50%).

CONCLUSIONS

This review highlights the diverse roles of NMPs in the care of people with mental illness. Whilst the limited evidence suggests a positive impact on patient care, more quantitative research is needed. Given the focus on nursing prescriber models in this review, along with rising mental health demand and continuing staff shortages, future research should prioritise exploring and evaluating the contribution of pharmacist NMP services as well other healthcare professionals' NMPs.

摘要

背景

非医学处方(NMP)资格将处方权扩展至护士、药剂师及其他专职医疗人员,被视为提高医疗效率和改善服务可及性的一种手段。然而,尽管非医学处方者(NMPs)在一些国家已被使用二十多年,但对于他们在心理健康领域的作用和影响却知之甚少。因此,本综述旨在梳理关于为精神疾病患者提供非医学处方服务的已发表研究证据。

方法

检索了2003年1月至2024年7月的五个电子数据库。还检查了已识别论文的参考文献列表以查找相关研究。纳入了在社区环境中探索为精神疾病和痴呆患者提供非医学处方服务的性质、影响及实施情况的全文原发性研究。

结果

在检索到的22547篇论文中,纳入了63项研究。其中,57项(90.4%)详细阐述了非医学处方者的性质(包括其所在的服务或团队、所开药物及主要职责),45项(71.4%)评估了服务的影响,16项(25.3%)探讨了影响服务实施和提供的因素。大多数研究来自美国(30/63,47.6%)或英国(27/63,42.8%)。单独研究护士(44/63,69.8%)、药剂师(16/63,25.3%)或由这两类专业人员组成的非医学处方模式(3/63,4.7%)。在英国和美国,非医学处方者最常开具的药物是抗抑郁药(分别为60%和54.5%)。尽管据报告,基于临床结果,由护士和药剂师处方者管理的患者病情得到了良好控制(分别为3/24,12.5%和3/13,23%),但很少有研究评估健康结果。英国的研究中普遍提到了与培训相关的服务提供障碍(4/9,44.4%),美国则报告了财务问题(2/4,50%)。

结论

本综述强调了非医学处方者在精神疾病患者护理中的多样作用。虽然有限的证据表明对患者护理有积极影响,但仍需要更多的定量研究。鉴于本综述关注护理处方者模式,以及心理健康需求不断增加和工作人员持续短缺的情况,未来的研究应优先探索和评估药剂师非医学处方服务以及其他医疗专业人员非医学处方服务的贡献。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3f32/12090459/6c094ee40a40/12888_2025_6938_Fig1_HTML.jpg

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