Seale J P, Hudson J A
South Med J. 1985 Apr;78(4):473-6. doi: 10.1097/00007611-198504000-00028.
We have reported a case with culture and serologic evidence of pulmonary infection with Petriellidium boydii treated with intravenous miconazole, resulting in dramatic symptomatic improvement, stabilization of x-ray changes, and clearing of Petriellidium on sputum culture. Although no biopsy was done to establish absolute diagnosis of invasive disease, and thus the results of this case cannot be taken as an absolute criterion for therapy, this may represent the first medical cure of pulmonary infection with this agent.
我们报告了一例经静脉注射咪康唑治疗的博伊德氏霉样真菌肺部感染病例,该病例有培养及血清学证据支持。治疗后症状显著改善,X线变化稳定,痰培养中博伊德氏霉样真菌转阴。尽管未进行活检以明确侵袭性疾病的绝对诊断,因此该病例结果不能作为治疗的绝对标准,但这可能代表了首例使用该药物治愈肺部感染的医学案例。