Nakano Takaaki, Ito Toshitaka
Department of Emergency Medicine, Shin-Yurigaoka General Hospital, Kanagawa, JPN.
Cureus. 2025 Apr 19;17(4):e82596. doi: 10.7759/cureus.82596. eCollection 2025 Apr.
Neurofibromatosis type 1 (NF1) is a genetic disorder involving an abnormality on chromosome 17, resulting in the production of the protein neurofibromin. Neurofibromin inhibits cell proliferation, and abnormalities in its encoding gene are hypothesized to trigger signals for proliferation, resulting in various lesions. Vascular fragility is a rare complication of NF1; however, ruptures of various vessels have also been reported. Here, we present a case of ulnar artery rupture treated endovascularly by puncturing the ipsilateral brachial artery, achieving excellent results.
1型神经纤维瘤病（NF1）是一种遗传性疾病，涉及17号染色体异常，导致神经纤维瘤蛋白的产生。神经纤维瘤蛋白抑制细胞增殖，其编码基因的异常被认为会触发增殖信号，从而导致各种病变。血管脆弱是NF1的一种罕见并发症；然而，也有各种血管破裂的报道。在此，我们报告一例通过穿刺同侧肱动脉进行血管内治疗的尺动脉破裂病例，取得了良好效果。
