Higa Shotaro, Nagano Takaaki, Ito Junji, Uejo Akino, Nakaema Moriyasu, Kise Yuya, Yamashiro Satoshi
Department of Thoracic and Cardiovascular Surgery, Graduate School of Medicine, University of the Ryukyus, Nishihara-cho, Okinawa, Japan.
Department of Radiology, Graduate School of Medicine, University of the Ryukyus, Nishihara-cho, Okinawa, Japan.
Ann Vasc Dis. 2021 Jun 25;14(2):168-172. doi: 10.3400/avd.cr.20-00174.
Neurofibromatosis type 1 (NF-1) is a rare disease known to cause vascular fragility. A case of a 59-year-old man with NF who had ruptures in three different arteries within a month is presented. The first rupture occurred in the right renal artery and was treated using a stent graft and embolization coils. The second and third ruptures occurred in an artery that had been compressed by a hematoma formed during the first bleed; both were embolized. In patients with NF-1, blood vessel fragility must be considered in treatment selection, especially when performing surgery or other invasive procedures near the great vessels.
1型神经纤维瘤病（NF-1）是一种已知会导致血管脆弱的罕见疾病。本文介绍了一例59岁患有NF-1的男性患者，该患者在一个月内三根不同的动脉发生破裂。首次破裂发生在右肾动脉，采用覆膜支架和栓塞弹簧圈进行治疗。第二次和第三次破裂发生在因首次出血形成的血肿压迫的动脉；两次均进行了栓塞治疗。对于NF-1患者，在选择治疗方案时必须考虑血管脆弱性，尤其是在大血管附近进行手术或其他侵入性操作时。
