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完全性心脏传导阻滞女性的妊娠结局:来自三级医疗中心的经验

Pregnancy Outcomes in Women with Complete Heart Block: Experience from a Tertiary Care Hospital.

作者信息

Vatsa Richa, Puleria Ranjana, Kulshrestha Vidushi, Aravindan Ajisha, Dhiman Soniya, Sharma K Aparna, Dadhwal Vatsla

机构信息

Department of Obstetrics and Gynecology, AIIMS, Room No 725, 7th Floor, Mother and Child Block, New Delhi, India.

Department of Anesthesiology, AIIMS, New Delhi, India.

出版信息

J Obstet Gynaecol India. 2025 Apr;75(Suppl 1):480-486. doi: 10.1007/s13224-024-02092-3. Epub 2025 Jan 11.

Abstract

BACKGROUND

Pregnancy in women with complete heart block (CHB) poses a substantial challenge. We share our experience of managing pregnancies in patients with CHB.

METHODS

In this case series, outcome of 12 pregnancies in 10 women with PPM is studied. The presentation, need for pacemaker, and cardiac intervention were noted in patients with CHB. Mode of delivery, obstetric complications, and neonatal outcomes were compared with 24 low-risk pregnancies. Data analysis was carried out using SPSS software.

RESULTS

Syncope was presenting symptoms in seven (70%) women. Three women (30%) presented for first time during pregnancy. Out of 12 pregnancies in 10 women, eight pregnancies in six patients had a permanent pacemaker (PPM) from the start of pregnancy. Among rest four patients without a PPM, two (50%) needed pacing, one needed PPM in the second trimester, and one had a temporary pacemaker implantation (TPI) at the time of delivery. Obstetric complications and period of gestation were similar between cases and controls. The cesarean delivery rate was higher in patients with CHB, but the difference was not significant (75% vs. 37.5%,  = 0.07). None of the patients needed intensive care unit care. Mean birth weight was lower among cases (2443 ± 442 g vs. 3167 ± 434 g), but the incidence of fetal growth restriction was not different between cases and controls.

CONCLUSION

Pregnancy in patients without PPM can be safely managed without pacing, with good obstetric and neonatal outcomes. Backup for TPI and/or cardiac interventions should be available during labor.

摘要

背景

患有完全性心脏传导阻滞(CHB)的女性怀孕带来了重大挑战。我们分享我们管理CHB患者妊娠的经验。

方法

在这个病例系列中,研究了10例接受永久性起搏器(PPM)治疗的女性的12次妊娠结局。记录了CHB患者的临床表现、起搏器需求和心脏干预情况。将分娩方式、产科并发症和新生儿结局与24例低风险妊娠进行比较。使用SPSS软件进行数据分析。

结果

晕厥是7名(70%)女性的主要症状。3名女性(30%)在孕期首次出现症状。10名女性的12次妊娠中,6名患者的8次妊娠从妊娠开始就有永久性起搏器(PPM)。其余4名没有PPM的患者中,2名(50%)需要起搏,1名在孕中期需要PPM,1名在分娩时植入了临时起搏器(TPI)。病例组和对照组的产科并发症和妊娠期相似。CHB患者的剖宫产率较高,但差异不显著(75%对37.5%,P = 0.07)。没有患者需要重症监护病房护理。病例组的平均出生体重较低(2443±442 g对3167±434 g),但病例组和对照组的胎儿生长受限发生率没有差异。

结论

没有PPM的患者妊娠可以在不进行起搏的情况下安全管理,产科和新生儿结局良好。分娩期间应具备TPI和/或心脏干预的备用措施。

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