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一项关于妊娠期间心脏病及母胎结局的前瞻性观察研究。

A Prospective Observational Study of Heart Diseases in Pregnancy and Fetomaternal Outcomes.

作者信息

Verma Tania, Manhas Gaurav Singh, Gupta Amita

机构信息

Department of Obstetrics and Gynecology, Government Medical College, Jammu, India.

出版信息

J Obstet Gynaecol India. 2025 Apr;75(Suppl 1):399-404. doi: 10.1007/s13224-024-02026-z. Epub 2024 Sep 9.

Abstract

OBJECTIVES

To determine the heart diseases during pregnancy the maternal and perinatal outcomes.

METHODS

This prospective observational study was conducted in a tertiary care hospital on 22,360 antenatal women registered to department of Obstetrics and Gynecology. The data recorded included demographic, clinical and obstetric characteristics, nature of the underlying cardiac lesions, and functional class. ECG and echocardiography were done to know the type and severity of cardiac lesions. Fetomaternal outcomes were assessed at follow-up clinical visits during second, third trimester, peripartum period, and at 6 weeks postpartum.

RESULTS

Heart diseases were present in 50(0.2%) women. Congenital heart diseases were present in 16(32%) patients, with most common being ventricular septal defect (VSD) in 7(14%) patients. Rheumatic heart diseases were present in 15(30%) patients, with most common being first degree heart block [4(8%)]. Mode of delivery was lower segment cesarean section in 32(64%) women and medical termination of pregnancy in 1(2%) patient. Postpartum complications were seen in 14(28%) patients; the most common being congestive cardiac failure in 5(10%) patients. Fetal complications were present in 21(42%) neonates which comprised of neonatal intensive care unit admission [13(26%)], intrauterine growth restriction in 7(14%), low birth weight in 6(12%), preterm in 5(10%), meconium aspiration syndrome in 4(8%) and intrauterine death in 3(4%) cases.

CONCLUSION

To conclude, heart diseases are present in 0.2% pregnant women with VSD rheumatic heart diseases being the commonest. Pregnant women with cardiac disease experience cardiac, obstetric, and fetal complications. Thus, cardiac diseases must be diagnosed to lower perinatal morbidity and death.

摘要

目的

确定孕期心脏病及其孕产妇和围产期结局。

方法

这项前瞻性观察性研究在一家三级护理医院对22360名登记到妇产科的产前妇女进行。记录的数据包括人口统计学、临床和产科特征、潜在心脏病变的性质以及心功能分级。进行心电图和超声心动图检查以了解心脏病变的类型和严重程度。在孕中期、孕晚期、围产期以及产后6周的随访临床就诊时评估母胎结局。

结果

50名(0.2%)妇女患有心脏病其中16名(32%)患者患有先天性心脏病最常见的是室间隔缺损(VSD)有7名(14%)患者。15名(30%)患者患有风湿性心脏病最常见的是一度房室传导阻滞[4名(8%)]。32名(64%)妇女的分娩方式为低位剖宫产1名(2%)患者进行了药物流产。14名(28%)患者出现产后并发症最常见的是5名(10%)患者发生充血性心力衰竭。21名(42%)新生儿出现胎儿并发症包括新生儿重症监护病房收治[13名(26%)]、7名(14%)胎儿宫内生长受限、6名(12%)低出生体重、5名(10%)早产、4名(8%)胎粪吸入综合征和3名(4%)宫内死亡。

结论

总之0.2%的孕妇患有心脏病其中VSD和风湿性心脏病最为常见。患有心脏病的孕妇会经历心脏、产科和胎儿并发症。因此必须诊断出心脏病以降低围产期发病率和死亡率。

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