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[多柔比星联合多药化疗治疗晚期复发性乳腺癌的初步结果]

[Initial results with PAC polychemotherapy in the treatment of advanced recurrent breast cancers].

作者信息

Schulz B O, Oberheuser F, Krebs D

出版信息

Zentralbl Gynakol. 1985;107(3):184-6.

PMID:4039095
Abstract

11 patients with advanced, recurrent mamma cancer were treated by a PAC polychemotherapy. The therapy was well tolerated, the incidence of side effects was low. All patients responded to therapy (7 NED, 3 CR, 1 PR). 2 patients died, one commited suicide, the other died after having developed hepatitis. Of the remaining 9 patients 7 survive recurrence free; medium follow up 20 months. These data are in accordance with results obtained by Kolarić et al. [2] and Forastiere et al. [1] who showed platinum to be effective in the treatment of mamma cancer.

摘要

11例晚期复发性乳腺癌患者接受了PAC联合化疗。该治疗耐受性良好,副作用发生率低。所有患者对治疗均有反应(7例无疾病证据,3例完全缓解,1例部分缓解)。2例患者死亡,1例自杀,另1例在患肝炎后死亡。其余9例患者中,7例无复发生存;中位随访20个月。这些数据与Kolarić等人[2]和Forastiere等人[1]的结果一致,他们表明铂类药物在乳腺癌治疗中有效。

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