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本文引用的文献

1
Effect of 1,3-diaminopropane on ornithine decarboxylase enzyme protein in thioacetamide-treated rat liver.1,3 -二氨基丙烷对硫代乙酰胺处理的大鼠肝脏中鸟氨酸脱羧酶蛋白的影响。
Biochem J. 1983 Dec 15;216(3):701-7. doi: 10.1042/bj2160701.
2
Cell-free synthesis of ornithine decarboxylase. Changes in mRNA activity in the liver of thioacetamide-treated rats.鸟氨酸脱羧酶的无细胞合成。硫代乙酰胺处理大鼠肝脏中mRNA活性的变化。
Eur J Biochem. 1984 Oct 1;144(1):35-9. doi: 10.1111/j.1432-1033.1984.tb08427.x.
3
Investigation of structure and rate of synthesis of ornithine decarboxylase protein in mouse kidney.小鼠肾脏中鸟氨酸脱羧酶蛋白的结构及合成速率研究。
Biochemistry. 1984 Jul 31;23(16):3777-83. doi: 10.1021/bi00311a033.
4
Regulation of ornithine decarboxylase activity by putrescine and spermidine in rat liver.腐胺和亚精胺对大鼠肝脏中鸟氨酸脱羧酶活性的调节
Biochem Biophys Res Commun. 1974 Nov 27;61(2):449-56. doi: 10.1016/0006-291x(74)90977-2.
5
Accumulation of ornithine decarboxylase-antizyme complex in HMOA cells.鸟氨酸脱羧酶-抗酶复合物在HMOA细胞中的积累。
Biochem J. 1985 Feb 1;225(3):689-97. doi: 10.1042/bj2250689.
6
Induction of a protein inhibitor to ornithine decarboxylase by the end products of its reaction.通过鸟氨酸脱羧酶反应的终产物诱导产生一种蛋白质抑制剂。
Proc Natl Acad Sci U S A. 1976 Jun;73(6):1858-62. doi: 10.1073/pnas.73.6.1858.
7
1,4-Diaminobutane (putrescine), spermidine, and spermine.1,4 - 二氨基丁烷（腐胺）、亚精胺和精胺。
Annu Rev Biochem. 1976;45:285-306. doi: 10.1146/annurev.bi.45.070176.001441.
8
Stabilization of ornithine decarboxylase in rat liver.
Biochim Biophys Acta. 1978 Jun 9;524(2):466-73. doi: 10.1016/0005-2744(78)90185-7.
9
Effects of aliphatic diamines on rat liver ornithine decarboxylase activity.脂肪族二胺对大鼠肝脏鸟氨酸脱羧酶活性的影响。
Biochem J. 1978 Mar 15;170(3):651-60. doi: 10.1042/bj1700651.
10
Ornithine decarboxylase antizyme is a normal component of uninduced H-35 cells and rat liver.鸟氨酸脱羧酶抗酶是未诱导的H-35细胞和大鼠肝脏的正常组成部分。
Eur J Biochem. 1977 Dec;81(3):545-50. doi: 10.1111/j.1432-1033.1977.tb11980.x.

抗酶在HTC细胞中鸟氨酸脱羧酶降解中的作用。

Role of antizyme in degradation of ornithine decarboxylase in HTC cells.

作者信息

Murakami Y, Hayashi S

出版信息

Biochem J. 1985 Mar 15;226(3):893-6. doi: 10.1042/bj2260893.

DOI:10.1042/bj2260893
PMID:4039135
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1144794/
Abstract

A good correlation was observed between the reciprocal of the half-life of ornithine decarboxylase (ODC) activity in the presence of cycloheximide and the relative amount of ODC-antizyme complex to total ODC (free ODC plus complexed ODC) activity in HTC cells examined at various times after cell dilution or change of medium. Pretreatment of cells with putrescine increased the relative amount of ODC-antizyme complex and decreased the half-life of ODC decay. These results suggested that antizyme plays a key role in ODC degradation.

摘要

在细胞稀释或更换培养基后的不同时间检测HTC细胞时，观察到在放线菌酮存在的情况下鸟氨酸脱羧酶（ODC）活性半衰期的倒数与ODC-抗酶复合物相对于总ODC（游离ODC加上复合ODC）活性的相对量之间存在良好的相关性。用腐胺预处理细胞可增加ODC-抗酶复合物的相对量，并缩短ODC降解的半衰期。这些结果表明抗酶在ODC降解中起关键作用。