Wang Can, Qiu Xiaoke, Mao Jiayu, Yang Xueli, Lin Yi, Zhao Jie, Li Qiuping
Wuxi School of Medicine, Jiangnan University, Wuxi, China.
Affiliated Hospital of Jiangnan University, Wuxi, China.
Nurs Health Sci. 2025 Jun;27(2):e70137. doi: 10.1111/nhs.70137.
This cross-sectional study aimed to investigate dyadic effects of micro-level (physical [PCS]/mental [MCS] health) and meso-level (dyadic coping/social support) factors on both subjective and objective social isolation in patient-spousal caregiver dyads with colorectal cancer (CRC), with hypothesized actor-partner interdependence effects. Data from 220 patient-caregiver dyads with CRC collected using validated instruments (General Alienation Scale, Lubben Social Network Scale-6, Medical Outcomes Study 12-item Short-Form version 2, Dyadic Coping Inventory, and Perceived Social Support Scale) were analyzed using the Actor-Partner Interdependence Model. Findings substantiated dyadic interdependence between subjective/objective social isolation and variables within dyads across micro- and meso-levels. Both micro-level (PCS/MCS) and meso-level (dyadic coping/social support) factors demonstrated significant actor effects on both subjective and objective social isolation experienced by patients and their partners. Patients' both micro-level (PCS/MCS) and meso-level (dyadic coping/social support) factors negatively influenced their partners' subjective and objective social isolation. No partner effect was identified from variables associated with spousal caregivers on patients' social isolation. These findings suggest that interventions targeting these variables could be effectively designed for patient-spousal caregiver dyads with CRC to address social isolation.
这项横断面研究旨在调查微观层面（身体[PCS]/心理[MCS]健康）和中观层面（二元应对/社会支持）因素对结直肠癌（CRC）患者-配偶照顾者二元组主观和客观社会隔离的二元效应，并假设存在行为者-伴侣相互依存效应。使用经过验证的工具（一般疏离感量表、鲁本社会网络量表-6、医学结局研究12项简表第2版、二元应对量表和感知社会支持量表）收集了220对CRC患者-照顾者二元组的数据，并使用行为者-伴侣相互依存模型进行了分析。研究结果证实了主观/客观社会隔离与微观和中观层面二元组内变量之间的二元相互依存关系。微观层面（PCS/MCS）和中观层面（二元应对/社会支持）因素对患者及其伴侣经历的主观和客观社会隔离均显示出显著的行为者效应。患者的微观层面（PCS/MCS）和中观层面（二元应对/社会支持）因素均对其伴侣的主观和客观社会隔离产生负面影响。未发现与配偶照顾者相关的变量对患者社会隔离有伴侣效应。这些发现表明，针对这些变量的干预措施可以有效地设计用于CRC患者-配偶照顾者二元组，以解决社会隔离问题。
