[情绪应激下易患心血管疾病的家兔神经系统中的乙酰胆碱酯酶和胆碱乙酰转移酶]
[Acetylcholinesterase and choline acetyltransferase in the nervous system of rabbits predisposed to cardiovascular disorders under emotional stress].
作者信息
Petrova N V, Fatranská M, Kvĕtnanský R, Belova T I, Kashtanov S I
出版信息
Biull Eksp Biol Med. 1985 Apr;99(4):415-8.
A study was made of the activity of acetylcholinesterase (AChE), cholinacetyl transferase (CAT), butyril cholinesterase (BCE) and water-soluble proteins in the structures of the CNS and in the autonomous ganglia in rabbits predisposed to cardiovascular disorders under emotional stress. It was established that unlike resistant animals, in those predisposed to cardiovascular disorders, the CAT content in the periphornical area of the hypothalamus did not differ from the control, the content of water-soluble proteins in the CNS structures and the ganglia remained unchanged either as compared with the control. The authors assume that the data obtained confirm a previously advanced concept of the involvement of the cholinergic system of the periphornical area of the hypothalamus in the maintenance of the stability of cardiovascular functions by regulation of the water-salt metabolism.
对易患心血管疾病的家兔在情绪应激下中枢神经系统结构和自主神经节中乙酰胆碱酯酶（AChE）、胆碱乙酰转移酶（CAT）、丁酰胆碱酯酶（BCE）及水溶性蛋白质的活性进行了研究。结果表明，与抗性动物不同，易患心血管疾病的家兔下丘脑外周区域的CAT含量与对照组无差异，中枢神经系统结构和神经节中的水溶性蛋白质含量与对照组相比也未发生变化。作者认为，所获得的数据证实了先前提出的关于下丘脑外周区域胆碱能系统通过调节水盐代谢参与维持心血管功能稳定性的概念。
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