Petrova N V, Fatranska M, Kvetnanskiĭ R, Belova T I, Kashtanov S I
Biull Eksp Biol Med. 1983 Aug;96(8):28-30.
To study the role of acetylcholine metabolism system in the mechanisms responsible for animals' resistance to emotional stress, the activity of acetylcholinesterase (AChE), butyrylcholinesterase and cholinacetyltransferase (CAT) was evaluated in brain structures and autonomous vegetative nervous system of rabbits after experimental emotional stress. In the course of experiments, arterial pressure and heart rate were recorded. The rabbits whose cardiovascular functions appeared to be resistant showed an increase in the activity of AChE and CAT in the perifocal area of the hypothalamus. It is suggested that the involvement of the perifocal area of the hypothalamus in the formation of the mechanisms responsible for the resistance is linked with the effects on water-salt metabolism.
为研究乙酰胆碱代谢系统在动物抵抗情绪应激机制中的作用,对实验性情绪应激后的家兔脑结构及自主植物神经系统中的乙酰胆碱酯酶(AChE)、丁酰胆碱酯酶和胆碱乙酰转移酶(CAT)活性进行了评估。实验过程中记录动脉血压和心率。心血管功能表现出抗性的家兔,其下丘脑灶周区域的AChE和CAT活性增加。提示下丘脑灶周区域参与抗性机制的形成与对水盐代谢的影响有关。