液相色谱-质谱联用分析氧化脂质的技术建议
Technical recommendations for analyzing oxylipins by liquid chromatography-mass spectrometry.
作者信息
Schebb Nils Helge, Kampschulte Nadja, Hagn Gerhard, Plitzko Kathrin, Meckelmann Sven W, Ghosh Soumita, Joshi Robin, Kuligowski Julia, Vuckovic Dajana, Botana Marina T, Sánchez-Illana Ángel, Zandkarimi Fereshteh, Das Aditi, Yang Jun, Schmidt Louis, Checa Antonio, Roche Helen M, Armando Aaron M, Edin Matthew L, Lih Fred B, Aristizabal-Henao Juan J, Miyamoto Sayuri, Giuffrida Francesca, Moussaieff Arieh, Domingues Rosário, Rothe Michael, Hinz Christine, Das Ujjalkumar Subhash, Rund Katharina M, Taha Ameer Y, Hofstetter Robert K, Werner Markus, Werz Oliver, Kahnt Astrid S, Bertrand-Michel Justine, Le Faouder Pauline, Gurke Robert, Thomas Dominique, Torta Federico, Milic Ivana, Dias Irundika H K, Spickett Corinne M, Biagini Denise, Lomonaco Tommaso, Idborg Helena, Liu Jun-Yan, Fedorova Maria, Ford David A, Barden Anne, Mori Trevor A, Kennedy Paul D, Maxey Kirk, Ivanisevic Julijana, Gallart-Ayala Hector, Gladine Cécile, Wenk Markus, Galano Jean-Marie, Durand Thierry, Stark Ken D, Barbas Coral, Garscha Ulrike, Gelhaus Stacy L, Ceglarek Uta, Flamand Nicolas, Griffin Julian L, Ahrends Robert, Arita Makoto, Zeldin Darryl C, Schopfer Francisco J, Quehenberger Oswald, Julian Randall, Nicolaou Anna, Blair Ian A, Murphy Michael P, Hammock Bruce D, Freeman Bruce, Liebisch Gerhard, Serhan Charles N, Köfeler Harald C, Jakobsson Per-Johan, Steinhilber Dieter, Gelb Michael H, Holčapek Michal, Andrew Ruth, Giera Martin, FitzGerald Garret A, Murphy Robert C, Newman John W, Dennis Edward A, Ekroos Kim, Milne Ginger L, Gijón Miguel A, Vesper Hubert W, Wheelock Craig E, O'Donnell Valerie B
机构信息
School of Mathematics and Natural Sciences, University of Wuppertal, Wuppertal, Germany.
Unit of Integrative Metabolomics, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.
出版信息
Sci Signal. 2025 May 20;18(887):eadw1245. doi: 10.1126/scisignal.adw1245.
Several oxylipins are potent lipid mediators that regulate diverse aspects of health and disease and whose quantitative analysis by liquid chromatography-mass spectrometry (LC-MS) presents substantial technical challenges. As members of the lipidomics community, we developed technical recommendations to ensure best practices when quantifying oxylipins by LC-MS.
几种氧化脂质是有效的脂质介质，可调节健康和疾病的各个方面，并且通过液相色谱 - 质谱联用（LC-MS）对其进行定量分析存在重大技术挑战。作为脂质组学领域的成员，我们制定了技术建议，以确保在通过LC-MS对氧化脂质进行定量时采用最佳实践。
Zotero 插件