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病例报告:黏膜下肌瘤宫腔镜子宫肌瘤切除术后弥漫性平滑肌瘤病的潜在风险。

Case report: Hidden risk of disseminated leiomyomatosis after hysteroscopic myomectomy for submucous fibroid.

作者信息

Puthiyidom Alphy, Shafi Asiyah, Ali Jijisha, Karamurzin Yevginiy, Khidhir Fatin

机构信息

Department of Obstetrics and Gynecology, Mediclinic Welcare Hospital, 2nd Street, Al Garhoud, Post Box 31600, Dubai, United Arab Emirates.

Department of Obstetrics and Gynecology, Mohammed Bin Rashid University of Medicine and Health Sciences, Building 14, Dubai Healthcare City, Post Box 505055, Dubai, United Arab Emirates.

出版信息

Int J Surg Case Rep. 2025 Jun;131:111439. doi: 10.1016/j.ijscr.2025.111439. Epub 2025 May 16.

Abstract

INTRODUCTION

Leiomyomatosis disseminata is a rare disease that can be challenging to diagnose. In this report, we present a case of Leiomyomatosis disseminata 1 year after hysteroscopic myomectomy with an intrauterine shaver.

PRESENTATION OF CASE

35-year-old woman presented with severe menorrhagia and multiple fibroids, including submucous fibroids. She underwent hysteroscopic myomectomy with an intrauterine shaver and a diagnostic second-look hysteroscopy one month later to assess for intrauterine adhesions. One year later, as part of her preparation for in-vitro fertilization (IVF), she was advised to undergo laparoscopic myomectomy and hysteroscopy for removal of an intramural fibroid and to evaluate the endometrial cavity. During laparoscopic exploration, multiple small seedling myoma-like lesions were identified on the uterine surface. Histopathological analysis confirmed that the lesions were consistent with fibroids. The patient successfully conceived after eight months via IVF and delivered by Caesarean section.

DISCUSSION

This case highlights the rare occurrence of disseminated leiomyomatosis following hysteroscopic myomectomies with an intrauterine shaver and resectoscope. The suspected mechanism involves the migration of myomatous fragments through the Fallopian tubes, resulting in the implantation of multiple small fibroid-like lesions.

CONCLUSION

This case suggests a need for heightened awareness of this potential complication, improving surgical technique for prevention and diligent postoperative evaluation for development of this condition.

摘要

引言

播散性平滑肌瘤病是一种罕见疾病,诊断颇具挑战性。在本报告中,我们呈现了一例在使用宫腔刨削器进行宫腔镜子宫肌瘤切除术后1年发生播散性平滑肌瘤病的病例。

病例介绍

一名35岁女性因严重月经过多及多发性肌瘤(包括黏膜下肌瘤)就诊。她接受了使用宫腔刨削器的宫腔镜子宫肌瘤切除术,并在1个月后进行了诊断性二次宫腔镜检查以评估宫腔粘连情况。1年后,作为其体外受精(IVF)准备工作的一部分,她被建议接受腹腔镜子宫肌瘤切除术及宫腔镜检查,以切除肌壁间肌瘤并评估子宫内膜腔。在腹腔镜探查过程中,在子宫表面发现了多个小的肌瘤样病灶。组织病理学分析证实这些病灶符合肌瘤特征。该患者在8个月后通过IVF成功受孕,并剖宫产分娩。

讨论

本病例突出了使用宫腔刨削器及电切镜进行宫腔镜子宫肌瘤切除术后发生播散性平滑肌瘤病的罕见情况。推测的机制是肌瘤碎片通过输卵管迁移,导致多个小肌瘤样病灶的种植。

结论

本病例提示需要提高对这种潜在并发症的认识,改进预防的手术技术,并在术后认真评估是否发生这种情况。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2d6d/12145974/f614d7ed2a7c/gr1.jpg

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