Doctoral Program in Pharmacy, Faculty of Pharmacy, Universitas Gadjah Mada, Yogyakarta, Indonesia.
Akademi Farmasi Surabaya, Surabaya, Indonesia.
J Prev Med Public Health. 2024 May;57(3):212-222. doi: 10.3961/jpmph.23.592. Epub 2024 Apr 25.
Epilepsy is a chronic disease that requires long-term treatment and intervention from health workers. Medication adherence is a factor that influences the success of therapy for patients with epilepsy. Therefore, this study aimed to analyze the role of pharmacists in improving the clinical outcomes of epilepsy patients, focusing on medication adherence.
A scoping literature search was conducted through the ScienceDirect, PubMed, and Google Scholar databases. The literature search included all original articles published in English until August 2023 for which the full text was available. This scoping review was carried out by a team consisting of pharmacists and neurologists following the Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) Extension for Scoping Reviews and the Joanna Briggs Institute guidelines, including 5 steps: identifying research questions, finding relevant articles, selecting articles, presenting data, and compiling the results.
The literature search yielded 10 studies that discussed pharmacist interventions for patients with epilepsy. Five articles described educational interventions involving drug-related counseling with pharmacists. Two articles focused on similar pharmacist interventions through patient education, both verbal and written. Three articles discussed an epilepsy review service, a multidisciplinary intervention program involving pharmacists and other health workers, and a mixed intervention combining education and training with therapy-based behavioral interventions.
Pharmacist interventions have been shown to be effective in improving medication adherence in patients with epilepsy. Furthermore, these interventions play a crucial role in improving other therapeutic outcomes, including patients' knowledge of self-management, perceptions of illness, the efficacy of antiepileptic drugs in controlling seizures, and overall quality of life.
癫痫是一种慢性病，需要卫生工作者进行长期的治疗和干预。药物依从性是影响癫痫患者治疗成功的一个因素。因此，本研究旨在分析药剂师在改善癫痫患者临床结局方面的作用，重点关注药物依从性。
通过 ScienceDirect、PubMed 和 Google Scholar 数据库进行了范围广泛的文献检索。文献检索包括截至 2023 年 8 月以英文发表的所有原始文章，并且可以获取全文。这项范围综述由一组药剂师和神经科医生按照系统评价和荟萃分析的首选报告项目（PRISMA）扩展范围综述以及乔安娜·布里格斯研究所指南进行，包括 5 个步骤：确定研究问题、寻找相关文章、选择文章、呈现数据和汇总结果。
文献检索共获得了 10 项讨论药剂师干预癫痫患者的研究。有 5 篇文章描述了涉及与药剂师进行药物相关咨询的教育干预。有 2 篇文章侧重于通过患者教育进行类似的药剂师干预，包括口头和书面形式。有 3 篇文章讨论了癫痫审查服务，这是一个涉及药剂师和其他卫生工作者的多学科干预计划，以及一种将教育和培训与基于治疗的行为干预相结合的混合干预。
已证明药剂师干预措施可有效提高癫痫患者的药物依从性。此外，这些干预措施在改善其他治疗结局方面发挥着关键作用，包括患者对自我管理的知识、对疾病的认知、抗癫痫药物控制癫痫发作的效果以及整体生活质量。
