Ovbiagele Bruce
Department of Neurology, University of California, 400 Parnassus, San Francisco, CA 94143, United States.
Equity Neurosci. 2025 Apr;1(1). doi: 10.1016/j.neuros.2025.100001. Epub 2025 Apr 22.
Over 3 billion people are affected by a neurological condition, which is now the leading cause of illness and disability worldwide. However, burden of neurological disease is unevenly distributed, with certain groups and regions being more affected than others. Neurological disorders disproportionately affect certain racial and ethnic communities (e.g., Black, Indigenous, and people of color), those in lower socioeconomic groups, individuals living in underserved geographies including rural areas and low-income countries, and other marginalized populations. These populations tend to have poorer neurological outcomes because they are adversely impacted by the social drivers of brain health including lack of access to care, minimal participation in pivotal neurological trials, and underrepresentation in neuroscience research careers. Equity neuroscience is a multidisciplinary academic field devoted to understanding inequities in the manifestations of nervous system health, from particles to people, at multiple interacting levels, with a bidirectional local to global scope. The Society for Equity Neuroscience (SEQUINS) founded in 2024 aims to enhance brain health around the world by improving equitable nervous system care and outcomes through research. SEQUIINS seeks to be the central and unifying global organization for equity neuroscientists; supporting, teaching, promoting, and applying high quality research to achieve equitable nervous system care and health. This paper highlights the rationale for establishing a dedicated community of equity neuroscientists and presents the mission, vision, and emerging academic activities of SEQUINS.
超过30亿人受到神经疾病的影响,神经疾病现已成为全球疾病和残疾的主要原因。然而,神经疾病的负担分布不均,某些群体和地区受到的影响比其他群体和地区更大。神经疾病对某些种族和族裔群体(如黑人、原住民和有色人种)、社会经济地位较低的群体、生活在包括农村地区和低收入国家在内的服务欠缺地区的个人以及其他边缘化人群的影响尤为严重。这些人群的神经疾病预后往往较差,因为他们受到大脑健康的社会驱动因素的不利影响,包括难以获得医疗服务、极少参与关键的神经学试验以及在神经科学研究职业中的代表性不足。公平神经科学是一个多学科的学术领域,致力于在多个相互作用的层面上,从微观粒子到宏观人群,以从局部到全球的双向视角,理解神经系统健康表现中的不平等现象。2024年成立的公平神经科学协会(SEQUINS)旨在通过研究改善神经系统的公平护理和治疗效果,从而提升全球的大脑健康水平。SEQUINS力求成为公平神经科学家的核心且统一的全球组织;支持、传授、推广并应用高质量研究,以实现神经系统的公平护理和健康。本文强调了建立一个专门的公平神经科学家群体的基本原理,并介绍了SEQUINS的使命、愿景和新兴的学术活动。