Department of Orthopedic Surgery, New England Baptist Hospital, Boston, MA.
Department of Trauma and Burn Surgery, John H Stroger Hospital of Cook County, Chicago, IL.
J Arthroplasty. 2022 Aug;37(8S):S836-S841. doi: 10.1016/j.arth.2022.01.049. Epub 2022 Jan 26.
Malnutrition affects patient outcomes after total joint arthroplasty (TJA). Although hypoalbuminemia has been used as a surrogate, there is no unanimous method for screening and assessing malnutrition. This study aimed to determine if malnutrition, as defined by the Geriatric Nutritional Risk Index (GNRI), is independently correlated with short-term (<30 days) postoperative complications and prognosis in patients undergoing TJA.
The 2016-2019 American College of Surgeons National Surgical Quality Improvement Program was queried for all patients aged >65 years who underwent TJA. Based on GNRI value, patients were divided into 3 groups: normal nutrition (GNRI >98), moderate malnutrition (GNRI 92-98), and severe malnutrition (GNRI <92). After adjusting for potential confounders, multivariable regression models were used to analyze the association between GNRI and patient outcomes.
A total of 191,087 patients were included in the study. Prevalence of malnutrition based on body mass index (<18.5 kg/m), albumin (<3.5 mg/dL), and GNRI (≤98) was 0.41% (784), 4.17% (7975), and 15.83% (30,258). Adjusted analysis showed that compared with normal nutrition, moderate and severe malnutrition status were associated with a higher rate of transfusion, readmission, and postoperative length of stay over 8 days (P < .05). Severe malnutrition was also associated with pneumonia, surgical site infection, urinary tract infection, sepsis, and revision surgery (P < .05).
Malnutrition, as defined by GNRI, is an independent predictor of adverse outcomes after TJA, including 30-day readmission, revision surgery, and increased length of stay. GNRI can be used to routinely screen and assess patient nutritional status before TJA and counsel patients and families appropriately.
Level 3: Retrospective Cohort Study.
营养不良会影响全关节置换术后(TJA)患者的预后。尽管低白蛋白血症已被用作替代指标,但目前尚无筛查和评估营养不良的统一方法。本研究旨在确定老年营养风险指数(GNRI)定义的营养不良是否与 TJA 患者短期(<30 天)术后并发症和预后独立相关。
查询了 2016 年至 2019 年美国外科医师学会国家外科质量改进计划中所有年龄>65 岁接受 TJA 的患者。根据 GNRI 值,患者分为 3 组:营养正常(GNRI>98)、中度营养不良(GNRI 92-98)和重度营养不良(GNRI<92)。在调整潜在混杂因素后,采用多变量回归模型分析 GNRI 与患者结局之间的关系。
共纳入 191087 例患者。基于体质指数(<18.5kg/m)、白蛋白(<3.5mg/dL)和 GNRI(≤98)的营养不良发生率分别为 0.41%(784 例)、4.17%(7975 例)和 15.83%(30258 例)。校正分析显示,与营养正常相比,中重度营养不良状态与输血、再入院和术后住院时间>8 天的发生率较高相关(P<0.05)。重度营养不良还与肺炎、手术部位感染、尿路感染、败血症和翻修手术相关(P<0.05)。
GNRI 定义的营养不良是 TJA 后不良结局的独立预测因素,包括 30 天再入院、翻修手术和住院时间延长。GNRI 可用于 TJA 前常规筛查和评估患者的营养状况,并适当对患者和家属进行咨询。
3 级:回顾性队列研究。