ChatGPT has garnered significant attention for its impressive capabilities across various domains, including medicine and mechanobiology. In order to facilitate the integration of ChatGPT into research, this paper explores the applications of ChatGPT in these domains, focusing on its usage in (1) reading and writing, (2) retrieval and knowledge management, and (3) computation, simulation, and visualization. Meanwhile, this study acknowledges the limitations and challenges associated with ChatGPT's usage. We investigate the interaction between ChatGPT and external tools in these applications and advocate for the integration of more powerful tools in these research areas into ChatGPT to further expand its potential applications in medicine and mechanobiology.