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符合罗马IV标准的肠易激综合征患者精神障碍的患病率:一项观察性研究。

Prevalence of psychiatric disorders in patients of irritable bowel syndrome fulfilling Rome IV criteria: An observational study.

作者信息

Bhattacharya Ranita, Pratima Kumari, Ambedkar Shivlok Narayan

机构信息

Department of Internal Medicine, VMMC and Safdarjung Hospital, New Delhi, India.

Department of Paediatrics, DDU Hospital, New Delhi, India.

出版信息

J Family Med Prim Care. 2025 Apr;14(4):1478-1485. doi: 10.4103/jfmpc.jfmpc_1196_23. Epub 2025 Apr 25.

Abstract

BACKGROUND

Rome IV criteria for the diagnosis of irritable bowel syndrome have been introduced recently hence, there are very few studies conducted to know the prevalence of IBS using these criteria. Prevalence of psychiatric disorder vary depending on criteria used. In view of these facts, this study was conducted to estimate prevalence of psychiatric disorders in patients of IBS fulfilling Rome IV criteria.

MATERIAL AND METHODS

Observational study at a tertiary care hospital in northern India. We included 100 patients aged ≥18 years who were diagnosed as irritable bowel syndrome fulfilling ROME IV criteria and assessed for different psychiatric manifestations using Patient health questionnaire after taking informed written consent.

RESULTS

75% of the IBS patient had more than one psychiatric comorbidity, while 25% had no psychiatric illness. The most common psychiatric comorbidity observed was generalized anxiety disorder 44%, followed by major depression in 38%, somatization disorder in 23%, panic disorder 18%, alcohol use disorder 18% and eating disorder. Statistically significant difference was found among patient having somatization disorder, eating disorder and alcohol use disorder among male and female.

CONCLUSION

The study emphasizes the need for regular counselling regarding psychiatric associations in IBS patients.

摘要

背景

罗马IV标准最近被用于肠易激综合征的诊断,因此,很少有研究使用这些标准来了解肠易激综合征的患病率。精神障碍的患病率因所使用的标准而异。鉴于这些事实,本研究旨在评估符合罗马IV标准的肠易激综合征患者中精神障碍的患病率。

材料与方法

在印度北部一家三级护理医院进行的观察性研究。我们纳入了100名年龄≥18岁、被诊断为符合罗马IV标准的肠易激综合征患者,并在获得知情书面同意后,使用患者健康问卷评估其不同的精神表现。

结果

75%的肠易激综合征患者有一种以上的精神共病,而25%没有精神疾病。观察到的最常见精神共病是广泛性焦虑障碍(44%),其次是重度抑郁症(38%)、躯体化障碍(23%)、惊恐障碍(18%)、酒精使用障碍(18%)和进食障碍。在男性和女性中,躯体化障碍、进食障碍和酒精使用障碍患者之间存在统计学显著差异。

结论

该研究强调了对肠易激综合征患者进行精神关联定期咨询的必要性。

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