Kawoos Yuman, Wani Zaid A, Kadla Showkat A, Shah Irfan A, Hussain Arshad, Dar M Maqbool, Margoob Mushtaq A, Sideeq Kouser
Department of Psychiatry, Government Medical College Srinagar, Srinagar, Jammu and Kashimir, India.
Department of Gastroenterology, Government Medical College Srinagar, Srinagar, Jammu and Kashimir, India.
J Neurogastroenterol Motil. 2017 Oct 30;23(4):555-560. doi: 10.5056/jnm16166.
BACKGROUND/AIMS: Irritable bowel syndrome (IBS) is a chronic psycho-physiological disorder. It is considered to be the most common functional gastrointestinal disorder, and about 50-90% of IBS patients have associated psychiatric co-morbidity. We aimed to study psychiatric co-morbidities in patients with IBS visiting a tertiary care center.
This was a cross-sectional case-control study conducted over a duration of one and a half years from January 2014 to July 2015. Patients were selected from the out-patient department of gastroenterology. About 160 patients with IBS who fulfilled the inclusion criteria and who gave written informed consent were selected as study cases. The healthy attendants of cases were selected as controls. A total of 200 controls were selected. Rome-III criteria were used to diagnose IBS. For diagnosing psychiatric disorders, we used the Mini International Neuropsychiatric Interview Schedule Plus.
Mean age of our cases and controls was 39.7 ± 11.4 and 37.7 ± 9.6 years, respectively. Females outnumbered males in our cases as well as their controls by a ratio of 2:1 approximately. Psychiatric disorders were seen in 84.4% of IBS patients as compared to 41.5% in controls. Major psychiatric disorders seen in our patients were generalized anxiety disorders (30.0%) and depression (28.0%).
The majority of patients with IBS who present to a tertiary care center have co-morbid psychiatric disorders. We need to screen these patients for such co-morbidities and develop a holistic approach for better outcome in such cases.
背景/目的：肠易激综合征（IBS）是一种慢性心理生理障碍。它被认为是最常见的功能性胃肠疾病，约50 - 90%的IBS患者伴有精神疾病共病。我们旨在研究在一家三级医疗中心就诊的IBS患者的精神疾病共病情况。
这是一项横断面病例对照研究，从2014年1月至2015年7月持续了一年半时间。患者从胃肠病科门诊选取。约160例符合纳入标准并签署书面知情同意书的IBS患者被选为研究病例。病例的健康陪护人员被选为对照。共选取了200名对照。采用罗马III标准诊断IBS。对于精神疾病的诊断，我们使用了迷你国际神经精神病学访谈量表升级版。
我们的病例组和对照组的平均年龄分别为39.7±11.4岁和37.7±9.6岁。病例组及其对照组中女性人数均约为男性的两倍。IBS患者中84.4%患有精神疾病，而对照组为41.5%。我们患者中主要的精神疾病为广泛性焦虑障碍（30.0%）和抑郁症（28.0%）。
到三级医疗中心就诊的大多数IBS患者患有共病精神疾病。我们需要对这些患者进行此类共病的筛查，并制定整体治疗方法以改善此类病例的治疗效果。
