Fyke F E, Seqard J B, Edwards W D, Miller F A, Reeder G S, Schattenberg T T, Schub C, Callahan J A, Tajik A J
J Am Coll Cardiol. 1985 Jun;5(6):1465-73. doi: 10.1016/s0735-1097(85)80364-8.
Experience with 30 consecutive patients who had a total of 32 primary cardiac tumors and who underwent two-dimensional echocardiographic examinations between January 1977 and June 1983 was reviewed. Most of the tumors were atrial myxomas (20 left and 4 right), and 30 were identified on echocardiography. Twenty-five patients, including 21 of 22 with atrial myxoma, underwent surgical resection on the basis of the echocardiographic examination, without preoperative angiocardiography. When the morphologic characteristics of the left atrial myxomas were studied statistically in relation to clinical abnormalities, large tumor size was most closely related to the number and type of associated clinical and laboratory abnormalities. The single exception was embolization, which correlated with echocardiographic tumor consistency. Since the introduction of two-dimensional echocardiography, the yearly incidence of cardiac tumor diagnosis at this clinic has increased several fold and the incidence of unexpected intraoperative diagnosis has been very low (one case). Echocardiography is the method of choice for clinical diagnosis. It has replaced angiocardiography for routine preoperative assessment, permits early diagnosis of cardiac neoplasms and provides insight into the pathophysiology of primary cardiac tumors.
回顾了1977年1月至1983年6月期间连续30例共患有32个原发性心脏肿瘤且接受二维超声心动图检查的患者的情况。大多数肿瘤为心房黏液瘤（左心房20个，右心房4个），其中30个通过超声心动图得以确诊。25例患者，包括22例心房黏液瘤患者中的21例，在未进行术前心血管造影的情况下，根据超声心动图检查结果接受了手术切除。当对左心房黏液瘤的形态学特征与临床异常情况进行统计学研究时，肿瘤体积较大与相关临床和实验室异常的数量及类型关系最为密切。唯一的例外是栓塞，它与超声心动图显示的肿瘤质地相关。自二维超声心动图应用以来，该诊所心脏肿瘤诊断的年发病率增加了数倍，术中意外诊断的发生率非常低（1例）。超声心动图是临床诊断的首选方法。它已取代心血管造影用于常规术前评估，能够早期诊断心脏肿瘤，并有助于深入了解原发性心脏肿瘤的病理生理学。
