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卵巢子宫内膜异位症的临床病理研究:囊性与非囊性类型的比较研究

Clinicopathologic investigation of ovarian endometriosis: a comparative study of cystic and non-cystic types.

作者信息

Tsukahara Y, Satoh M, Kato J, Fukamatsu Y, Funamoto H, Kitahara T, Fukuta T

出版信息

Nihon Sanka Fujinka Gakkai Zasshi. 1985 May;37(5):751-7.

PMID:4039743
Abstract

This clinicopathologic study involved 129 patients with ovarian endometriosis. All the lesions from the patients were classified macroscopically into two types being either cystic or non-cystic. The results are as follows. Endometriotic lesions were bilateral in 58 cases and unilateral in 71 cases. The average age of the patients was 38.8 and gravidity 1.8, with 43.1% of them being infertilite. In 12.2, 45.4 and 84.6% of them, irregular menstruation, hypermenorrhea, and dysmenorrhea were recorded, respectively. Regarding complicated lesions, 49 patients had fibroid, 33 uterine adenomyosis, and 13 rectocervical endometriosis. Of the 129 cases, 61.3% were regarded as of the cystic type, 30.2% as of the non-cystic type, and 8.5% as of the cystic/non-cystic type. The average ages were 35.5 and 41.6 years for cystic and non-cystic types, respectively. The incidence of each type of complicated lesion mentioned above was greater in the non-cystic type than that in the cystic type. The pathogenetic investigation suggested that cystic endometriosis in the ovary might mainly be ascribed to the endometrioid metaplasia of the celomic epithelium and that non-cystic endometriosis might occasionally originate from metastasis or implantation of endometrial tissues. In addition to this, the lesions which were histologically diagnosed as endometriosis might sometimes include obsolete follicle cysts undergoing luteinization.

摘要

本临床病理研究纳入了129例卵巢子宫内膜异位症患者。将所有患者的病变在宏观上分为囊性和非囊性两种类型。结果如下。子宫内膜异位病变双侧者58例,单侧者71例。患者的平均年龄为38.8岁,平均妊娠次数为1.8次,其中43.1%为不孕患者。分别有12.2%、45.4%和84.6%的患者记录有月经不调、月经过多和痛经。关于合并病变,49例患者有子宫肌瘤,33例有子宫腺肌病,13例有直肠宫颈子宫内膜异位症。在129例病例中,61.3%被视为囊性类型,30.2%为非囊性类型,8.5%为囊性/非囊性类型。囊性和非囊性类型的平均年龄分别为35.5岁和41.6岁。上述每种合并病变的发生率在非囊性类型中高于囊性类型。病因学研究表明,卵巢囊性子宫内膜异位症可能主要归因于间皮细胞的子宫内膜样化生,而非囊性子宫内膜异位症可能偶尔起源于子宫内膜组织的转移或种植。除此之外,组织学诊断为子宫内膜异位症的病变有时可能包括正在经历黄素化的陈旧性卵泡囊肿。

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Clinicopathologic investigation of ovarian endometriosis: a comparative study of cystic and non-cystic types.卵巢子宫内膜异位症的临床病理研究:囊性与非囊性类型的比较研究
Nihon Sanka Fujinka Gakkai Zasshi. 1985 May;37(5):751-7.
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引用本文的文献

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Pathogenesis of ovarian clear cell adenofibroma, atypical proliferative (borderline) tumor, and carcinoma: clinicopathologic features of tumors with endometriosis or adenofibromatous components support two related pathways of tumor development.卵巢透明细胞腺纤维瘤、非典型增生(交界性)肿瘤和癌的发病机制:具有子宫内膜异位症或腺纤维瘤成分的肿瘤的临床病理特征支持肿瘤发展的两种相关途径。
J Cancer. 2011 Feb 21;2:94-106. doi: 10.7150/jca.2.94.