提高自闭症谱系障碍个体的进餐接受度（AUT-MENU项目）：一项双中心干预研究方案

Improving Meal Acceptance of Individuals With Autism Spectrum Disorder (AUT-MENU Project): Protocol for a Bicentric Intervention Study.

作者信息

Conti Maria Vittoria, Breda Chiara, Basilico Sara, Zambon Ilaria, Sofroniou Angeliki, Ruggeri Stefania, Scalvedi Maria Luisa, Cena Hellas

机构信息

Laboratory of Dietetics and Clinical Nutrition, Department of Public Health, Experimental and Forensic Medicine, University of Pavia, Pavia, Italy.

Research Centre for Food and Nutrition, CREA, Rome, Italy.

出版信息

JMIR Res Protoc. 2025 May 21;14:e57507. doi: 10.2196/57507.

DOI:10.2196/57507

PMID:40397941

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12138289/

Abstract

BACKGROUND

Individuals with autism spectrum disorder (ASD) often exhibit low dietary diversity due to food selectivity, leading to various forms of malnutrition, such as obesity or micronutrient deficiencies.

OBJECTIVE

The main objective of the AUT-MENU project is to improve meal acceptance among individuals with ASD. A secondary goal is to evaluate the effectiveness of a nutrition education course for parents of enrolled participants to reduce food selectivity.

METHODS

The study is a bicentric intervention conducted in 3 care centers (Pavia and Milan) and 1 secondary school (Rome), involving approximately 200 participants with ASD aged 3 to 35 years. The study consists of an observational phase (T0) and an intervention phase (T1). At T0, biographical data, clinical characteristics, and dietary patterns of participants are collected. Based on T0 findings and existing nutritional recommendations for individuals with ASD, targeted menus are developed and tested. At T1, the same assessment tools used at T0 will be applied to evaluate intervention effects. Additionally, a nutrition education course for caregivers will be implemented between T0 and T1, with a pre- and postcourse knowledge questionnaire to assess its effectiveness.

RESULTS

Due to different timelines depending on the centers and schools involved, participant enrollment and data collection will take place at different times between Pavia, Milan, and Rome. In September 2024, enrollment was held in the Pavia and Milan care centers for a total of 74 participants enrolled. In Rome, the enrollment phase has not yet started; activities are expected to be carried out similar to those in Pavia and Milan.

CONCLUSIONS

The AUT-MENU study is expected to yield significant insights and improvements in meal acceptance among individuals with ASD, particularly through the introduction of targeted menus in collective catering settings both in care centers and schools.

TRIAL REGISTRATION

ClinicalTrials.gov NCT06266377; https://clinicaltrials.gov/study/NCT06266377.

INTERNATIONAL REGISTERED REPORT IDENTIFIER (IRRID): DERR1-10.2196/57507.

摘要

背景

自闭症谱系障碍（ASD）患者常因食物选择性而饮食多样性较低，导致各种形式的营养不良，如肥胖或微量营养素缺乏。

目的

AUT-MENU项目的主要目标是提高ASD患者对膳食的接受度。次要目标是评估为已登记参与者的家长提供的营养教育课程对减少食物选择性的有效性。

方法

该研究是一项在3个护理中心（帕维亚和米兰）和1所中学（罗马）进行的双中心干预研究，涉及约200名年龄在3至35岁的ASD患者。该研究包括一个观察阶段（T0）和一个干预阶段（T1）。在T0阶段，收集参与者的传记数据、临床特征和饮食模式。根据T0阶段的研究结果以及针对ASD患者的现有营养建议，制定并测试针对性的菜单。在T1阶段，将应用与T0阶段相同的评估工具来评估干预效果。此外，将在T0和T1阶段之间为护理人员开展营养教育课程，并通过课前和课后知识问卷来评估其有效性。