Kunkel M, Gärtner L, Oberender H
Z Gesamte Inn Med. 1985 Apr 1;40(7):189-93.
There are two serological types of herpes simplex virus, HSV-1 and HSV-2. The types can be differentiated by different methods. After a primary infection HSV reaches the sensory ganglions by the way of peripheral nervous tracts. The virus remains for life in the ganglion as virus genome. After activation and return movement a new infection can appear. A lot of various diseases are caused by primary infection, reactivation or reinfection. The diagnosis in herpes virus diseases includes the detection of virus or viral antigens and the demonstration of specific antibodies against HSV. Effective antiviral drugs are available for chemotherapy of HSV-infection. Acyclovir is a beneficial drug without toxic secondary effects. The prevalence of HSV-antibodies in the population is very high.
单纯疱疹病毒有两种血清学类型，即HSV - 1和HSV - 2。这两种类型可通过不同方法进行区分。初次感染后，HSV通过外周神经通路到达感觉神经节。病毒以病毒基因组的形式在神经节中终生存在。激活并逆向移动后，可能会出现新的感染。许多不同的疾病是由初次感染、再激活或再次感染引起的。疱疹病毒疾病的诊断包括病毒或病毒抗原的检测以及针对HSV的特异性抗体的证明。有有效的抗病毒药物可用于HSV感染的化疗。阿昔洛韦是一种有益的药物，没有毒性副作用。人群中HSV抗体的流行率非常高。
