光化学同二聚作用作为天然产物合成中的关键步骤。
Photochemical Homodimerization as a Key Step in Natural Product Synthesis.
作者信息
Plachinski Ellie F, Yoon Tehshik P
机构信息
Department of Chemistry, University of Wisconsin-Madison, 1101 University Avenue, Madison WI 53706 United States.
出版信息
Tetrahedron. 2025 Sep 1;183. doi: 10.1016/j.tet.2025.134706. Epub 2025 May 8.
Abstract
Photochemical dimerizations constitute a relatively simple but important class of bimolecular reactions. Nature produces several classes of dimeric natural products, some of which appear to be arise from radical or excited-state coupling reactions that could be photochemically initiated. This review focuses on natural products syntheses that exploit these photochemical dimerization reactions; selected total syntheses are discussed as examples, with particular attention given to the photochemical key step and its stereoselectivity.
摘要
光化学二聚反应构成了一类相对简单但重要的双分子反应。自然界产生了几类二聚体天然产物，其中一些似乎源于可能由光化学引发的自由基或激发态偶联反应。本综述重点关注利用这些光化学二聚反应的天然产物合成；以选定的全合成作为例子进行讨论，特别关注光化学关键步骤及其立体选择性。
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