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肝硬化的皮肤表现:一例肠病性肢端皮炎

Cutaneous Implications of Liver Cirrhosis: A Case of Acrodermatitis Enteropathica.

作者信息

Shuaibi Sameera, AlSejari Najat, Farhud Samer, Nguyen Jeanne, McIntyre Caley

机构信息

Internal Medicine, Ochsner Clinic Foundation, New Orleans, USA.

Internal Medicine, Jaber Hospital, Kuwait City, KWT.

出版信息

Cureus. 2025 Apr 21;17(4):e82734. doi: 10.7759/cureus.82734. eCollection 2025 Apr.

Abstract

Acrodermatitis enteropathica (AE) is characterized by a constellation of symptoms that result from a deficiency in serum zinc levels. The commonest cause of AE is hereditary autosomal recessive genetic mutations that impair zinc absorption in the small intestine, while acquired causes come second. Liver disease has been implicated in the development of acquired zinc deficiency. Herein, we present a case of AE with severe exfoliative skin lesions that occurred secondary to decompensated liver cirrhosis.

摘要

肠病性肢端皮炎(AE)的特征是一系列由血清锌水平缺乏导致的症状。AE最常见的病因是遗传性常染色体隐性基因突变,该突变会损害小肠对锌的吸收,而获得性病因则居其次。肝脏疾病被认为与获得性锌缺乏的发生有关。在此,我们报告一例因失代偿期肝硬化继发的、伴有严重剥脱性皮肤损害的AE病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e3a1/12094836/6f825344f991/cureus-0017-00000082734-i01.jpg

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