Tavano Fabio T, Silva Alex R B, Castro Charlles H M, de Medeiros Pinheiro Marcelo, Szejnfeld Vera Lúcia
Rheumatology Division, Escola Paulista de Medicina/Universidade Federal de São Paulo (EPM/UNIFESP), Rua Botucatu, nº 740, São Paulo, 04023-062, Brazil.
Osteoporos Int. 2025 May 22. doi: 10.1007/s00198-025-07528-8.
This study examined the incidence trend of humeral fragility fractures among Brazilian adults over age 50 admitted to public hospitals from 2004 to 2013. The findings revealed significant increases in annual rates of humeral fractures, especially among elderly women and patients from the Southeast region. It is essential for the implementation of effective public health policies.
Humeral fragility fractures are associated with a significant health care burden, especially those requiring surgeries. With limited epidemiological data, the present study aimed to determine the annual rate of humeral fractures requiring hospitalization in the public health system among Brazilian adults ≥ 50 years-old between 2004 and 2013. A secular trend analysis of the humeral fracture rate was also investigated.
This was a retrospective, observational study of admissions in the Brazilian public hospitals from 2004 to 2013, including patients 50 years and older admitted for primary treatment with a primary diagnosis of humerus fractures (ICD-10 S-42.2, S-42.3 and S-42.4) associated with low-trauma events. The annual rates of humeral fractures were calculated according to sex, age, and geographic region, and a linear regression analysis was used to determine secular trends.
Most of the total of 34,071 humeral fractures occurred in women (59.21%), among the age group 50-59 years (33.14%) and in residents from the Southeast region (60%). The average annual rate of humeral fractures for the overall population, women and men was 12.56, 14.11 and 10.85 per 100,000 inhabitants-years, respectively. Secular trend analysis showed a 21.18% significant increase in the crude humeral fracture rate among women (P = 0.024). There was a reduction in humeral fracture rate between 2004 and 2008 followed by an increase from 2009 to 2013. The Southeast region had the highest fracture rates with a significant 11.95% increase in secular trend for women (P = 0.031).
Hospitalizations for humeral fractures in Brazil increased significantly from 2004 to 2013, particularly among elderly women and those living in the most densely populated Southeast region. As osteoporotic humeral fractures are often associated with an increased risk of subsequent major osteoporotic fractures, especially hip fractures, understanding this trend is essential for implementing effective public health policies.
Level III-Retrospective Design Using a Large Database. Prognosis Study.
本研究调查了2004年至2013年期间入住公立医院的50岁以上巴西成年人肱骨脆性骨折的发病趋势。研究结果显示,肱骨骨折的年发病率显著上升,尤其是老年女性和来自东南部地区的患者。这对于实施有效的公共卫生政策至关重要。
肱骨脆性骨折会带来重大的医疗负担,尤其是那些需要手术治疗的骨折。由于流行病学数据有限,本研究旨在确定2004年至2013年期间巴西50岁及以上成年人在公共卫生系统中因肱骨骨折需住院治疗的年发病率。同时还对肱骨骨折率进行了长期趋势分析。
这是一项对2004年至2013年巴西公立医院入院病例的回顾性观察研究,纳入年龄在50岁及以上、因与低创伤事件相关的肱骨骨折(国际疾病分类第十版S-42.2、S-42.3和S-42.4)而接受初次治疗的患者。根据性别、年龄和地理区域计算肱骨骨折的年发病率,并采用线性回归分析来确定长期趋势。
在总共34071例肱骨骨折中,大多数发生在女性(59.21%)、50至59岁年龄组(33.14%)以及东南部地区的居民(60%)。总体人群、女性和男性的肱骨骨折平均年发病率分别为每10万居民年12.56例、14.1例和10.85例。长期趋势分析显示,女性的粗肱骨骨折率显著上升了21.18%(P = 0.024)。2004年至2008年肱骨骨折率有所下降,随后从2009年至2013年上升。东南部地区的骨折率最高,女性的长期趋势显著上升了11.95%(P = 0.031)。
2004年至2013年期间,巴西因肱骨骨折住院的人数显著增加,尤其是老年女性和居住在人口最密集的东南部地区的人群。由于骨质疏松性肱骨骨折往往与随后发生重大骨质疏松性骨折(尤其是髋部骨折)的风险增加相关,了解这一趋势对于实施有效的公共卫生政策至关重要。
三级——使用大型数据库的回顾性设计。预后研究。